Small Nuclear Ribonucleoprotein Recombinant Protein | SNRPA recombinant protein
Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
Small Nuclear Ribonucleoprotein; Recombinant Human Small Nuclear Ribonucleoprotein Polypeptide A; SNRPA Human; Small Nuclear Ribonucleoprotein Polypeptide A Human Recombinant; U1 small nuclear ribonucleoprotein A; U1 snRNP A; U1-A; U1A; SNRPA; Mud1; SNRPA recombinant protein
Host
Sf9 Insect Cells
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
SNRPA is supplied in 20mM HEPES buffer pH-7.6, 250mM NaCl and 20% glycerol.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence Length
98
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Avoid multiple freeze-thaw cycles.
Related Product Information for SNRPA recombinant protein
Description: SNRPA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a calculated molecular mass of 32,102 Dalton. SNRPA is expressed with a -6x His tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.
Introduction: SNRPA associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is essential for splicing. The SNRPA protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and is involved in the coupling of splicing and polyadenylation. SNRPA binds stem loop II of U1 snRNA. SNRPA is the first snRNP to interact with pre-mRNA. This interaction is vital for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP.
Product Categories/Family for SNRPA recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
small nuclear ribonucleoprotein
NCBI Official Symbol
DQ04_00451130
NCBI Protein Information
small nuclear ribonucleoprotein
Protein Family
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Product Notes
The SNRPA (Catalog #AAA146310) is a Recombinant Protein produced from Sf9 Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Small Nuclear Ribonucleoprotein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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