Actin Related Protein 2/3 Complex Recombinant Protein | ARPC2 recombinant protein
Recombinant Human Actin Related Protein 2/3 Complex, Subunit 2
Sterile Filtered colorless solution.
Introduction: Actin-related protein 2/3 complex subunit 2 (ARPC2), is a part of the Rho family of small GTPases and one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. Nevertheless, the exact role of the protein (the p34 subunit) has yet to be determined.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Uniprot Description
ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family.
Protein type: Motility/polarity/chemotaxis; Actin-binding; Cytoskeletal
Chromosomal Location of Human Ortholog: 2q36.1
Cellular Component: Golgi apparatus; neuron projection; Arp2/3 protein complex; focal adhesion; cytoplasm; leading edge; plasma membrane; synapse; cytosol; endosome; actin cytoskeleton
Molecular Function: actin filament binding; protein binding; structural constituent of cytoskeleton; kinesin binding
Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility
Research Articles on ARPC2
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Product Notes
The ARPC2 arpc2 (Catalog #AAA145518) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMIL LEVN NRIIEETLAL KFENAAAGNK PEAVEVTFAD FDGVLYHISN PNGDKTKVMV SISLKFYKEL QAHGADELLK RVYGSFLVNP ESGYNVSLLY DLENLPASKD SIVHQAGMLK RNCFASVFEK YFQFQEEGKE GENRAVIHYR DDETMYVESK KDRVTVVFST VFKDDDDVVI GKVFMQEFKE GRRASHTAPQ VLFSHREPPL ELKDTDAAVG DNIGYITFVL FPRHTNASAR DNTINLIHTF RDYLHYHIKC SKAYIHTRMR AKTSDFLKVL NRARPDAEKK EMKTITGKTF SSR. It is sometimes possible for the material contained within the vial of "Actin Related Protein 2/3 Complex, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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