Nuclease-sensitive element-binding protein 1 (YBX1) Recombinant Protein | YBX1 recombinant protein
Recombinant Rabbit Nuclease-sensitive element-binding protein 1 (YBX1)
NCBI and Uniprot Product Information
Uniprot Description
Mediates pre-mRNA alternative splicing regulation. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'). Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds to splice sites in pre-mRNA and regulates splice site selection. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro (). Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors.
Research Articles on YBX1
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Product Notes
The YBX1 ybx1 (Catalog #AAA1453079) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-324, Full length protein. The amino acid sequence is listed below: SSEAETQQPP AAPPAAPALS AAETKPGTTG SGAGSGGPGG LTSAAPAGGD KKVIATKVLG TVKWFNVRNG YGFINRNDTK EDVFVHQTAI KKNNPRKYLR SVGDGETVEF DVVEGEKGAE AANVTGPGGV PVQGSKYAAD RNHYRRYPRR RGPPRNYQQN YQNSESGEKN EGSESAPEGQ AQQRRPYRRR RFPPYYMRRP YGRRPQYSNP PVQGEVMEGA DNQGAGEQGR PVRQNMYRGY RPRFRRGPPR QRQPREDGNE EDKENQGDET QGQQPPPSRY RRNFNYRRRR PDNPKPQDGK ETKAADPPAE NSSAPEAEQG GAE. It is sometimes possible for the material contained within the vial of "Nuclease-sensitive element-binding protein 1 (YBX1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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