Intraflagellar transport protein 140 homolog (IFT140) Recombinant Protein | IFT140 recombinant protein

Recombinant Human Intraflagellar transport protein 140 homolog (IFT140) , partial

• Gene Names: IFT140; RP80; MZSDS; SRTD9; WDTC2; gs114; c305C8.4; c380F5.1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Intraflagellar transport protein 140 homolog (IFT140); Recombinant Human Intraflagellar transport protein 140 homolog (IFT140); partial; IFT140 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 656

• Species: Human
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 41281447
• NCBI GeneID: 9742
• NCBI Accession #: NP_055529.2
• NCBI GenBank Nucleotide #: NM_014714.3
• UniProt Accession #: Q96RY7; O60332; Q9UG52; A2A2A8; D3DU75
• Molecular Weight: 75,572 Da
• NCBI Official Full Name: intraflagellar transport protein 140 homolog
• NCBI Official Synonym Full Names: intraflagellar transport 140
• NCBI Official Symbol: IFT140
• NCBI Official Synonym Symbols: RP80; MZSDS; SRTD9; WDTC2; gs114; c305C8.4; c380F5.1
• NCBI Protein Information: intraflagellar transport protein 140 homolog
• UniProt Protein Name: Intraflagellar transport protein 140 homolog
• Protein Family: Intraflagellar transport protein
• UniProt Gene Name: IFT140
• UniProt Synonym Gene Names: KIAA0590; WDTC2

NCBI Description

This gene encodes one of the subunits of the intraflagellar transport (IFT) complex A. Intraflagellar transport is involved in the genesis, resorption and signaling of primary cilia. The primary cilium is a microtubule-based sensory organelle at the surface of most quiescent mammalian cells, that receives signals from its environment, such as the flow of fluid, light or odors, and transduces those signals to the nucleus. Loss of the corresponding protein in mouse results in renal cystic disease. [provided by RefSeq, Jun 2012]

Uniprot Description

Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Plays a pivotal role in proper development and function of ciliated cells. Involved in ciliogenesis and cilia maintenance (PubMed:22503633). May play a role in ciliary assembly. Required for the development and maintenance of the outer segments of rod and cone photoreceptor cells. Plays a role in maintenance and the delivery of opsin to the outer segment of photoreceptor cells ().