Peroxisomal D3,D2-Enoyl-CoA Isomerase Recombinant Protein | PECI recombinant protein
Recombinant Human Peroxisomal D3,D2-Enoyl-CoA Isomerase
Gene Names
ECI2; DRS1; PECI; ACBD2; DRS-1; HCA88; dJ1013A10.3
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Peroxisomal D3; D2-Enoyl-CoA Isomerase; Recombinant Human Peroxisomal D3; PECI Human; D2-Enoyl-CoA Isomerase Human Recombinant; EC 5.3.3.8; ACBD2; DRS1; HCA88; PECI; Peroxisomal 3; 2-trans-enoyl-CoA isomerase; Dodecenoyl-CoA isomerase; Delta(3); delta(2)-enoyl-CoA isomerase; D3; D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; DRS-1; Hepatocellular carcinoma-associated antigen 88; Renal carcinoma antigen NY-REN-1; KIAA0536; dJ1013A10; PECI recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
PECI Human solution containing 20mM Trsi pH-8, & 10% glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MNRTAMRASQ KDFENSMNQV KLLKKDPGNE VKLKLYALYK QATEGPCNMP KPGVFDLINK AKWDAWNALG SLPKEAARQN YVDLVSSLSP SLESSSQVEP GTDRKSTGFE TLVVTSEDGI TKIMFNRPKK KNAINTEMYH EIMRALKAAS KDDSIITVLT GNGDYYSSGN DLTNFTDIPP GGVEEKAKNN AVLLREFVGC FIDFPKPLIA VVNGPAVGIS VTLLGLFDAV YASDRATFHT PFSHLGQSPE GCSSYTFPKI MSPAKATEML IFGKKLTAGE ACAQGLVTEV FPDSTFQKEV WTRLKAFAKL PPNALRISKE VIRKREREKL HAVNAEECNV LQGRWLSDEC TNAVVNFLSR KSKL
Sequence Length
364
Preparation and Storage
PECI Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.
Related Product Information for PECI recombinant protein
Description: PECI Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 384 amino acids (1-364 a.a.) and having a molecular mass of 42.3 kDa. The PECI is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Introduction: PECI is an enzyme that localized to the peroxisomal matrix and encloses one ACB (acyl-CoA-binding) domain. PECI is expressed abundantly in liver, heart and skeletal muscle. PECI functions to catalyze the isomerization of both 3-cis and 3-trans double bonds into the 2-trans form in an array of enoyl-CoA species. PECI takes part in the beta-oxidation of unsaturated fatty acids.
Introduction: PECI is an enzyme that localized to the peroxisomal matrix and encloses one ACB (acyl-CoA-binding) domain. PECI is expressed abundantly in liver, heart and skeletal muscle. PECI functions to catalyze the isomerization of both 3-cis and 3-trans double bonds into the 2-trans form in an array of enoyl-CoA species. PECI takes part in the beta-oxidation of unsaturated fatty acids.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,609 Da
NCBI Official Full Name
enoyl-CoA delta isomerase 2, mitochondrial isoform 1
NCBI Official Synonym Full Names
enoyl-CoA delta isomerase 2
NCBI Official Symbol
ECI2
NCBI Official Synonym Symbols
DRS1; PECI; ACBD2; DRS-1; HCA88; dJ1013A10.3
NCBI Protein Information
enoyl-CoA delta isomerase 2, mitochondrial; D3,D2-enoyl-CoA isomerase; DBI-related protein 1; acyl-Coenzyme A binding domain containing 2; delta(3),delta(2)-enoyl-CoA isomerase; diazepam-binding inhibitor-related protein 1; dodecenoyl-CoA isomerase; hepatocellular carcinoma-associated antigen 88; peroxisomal 3,2-trans-enoyl-CoA isomerase; peroxisomal D3,D2-enoyl-CoA isomerase; renal carcinoma antigen NY-REN-1
UniProt Protein Name
Enoyl-CoA delta isomerase 2, mitochondrial
UniProt Gene Name
ECI2
UniProt Synonym Gene Names
DRS1; HCA88; PECI; D3,D2-enoyl-CoA isomerase; DBI-related protein 1; pECI
UniProt Entry Name
ECI2_HUMAN
NCBI Description
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011]
Uniprot Description
PECI: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 5.3.3.8; Lipid Metabolism - fatty acid; Isomerase
Chromosomal Location of Human Ortholog: 6p24.3
Cellular Component: nucleoplasm; peroxisomal matrix; intracellular membrane-bound organelle; membrane; mitochondrion
Molecular Function: acyl-CoA binding; dodecenoyl-CoA delta-isomerase activity; receptor binding
Biological Process: metabolic process; fatty acid catabolic process
Research Articles on PECI
Similar Products
Product Notes
The PECI eci2 (Catalog #AAA144029) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MNRTAMRASQ KDFENSMNQV KLLKKDPGNE VKLKLYALYK QATEGPCNMP KPGVFDLINK AKWDAWNALG SLPKEAARQN YVDLVSSLSP SLESSSQVEP GTDRKSTGFE TLVVTSEDGI TKIMFNRPKK KNAINTEMYH EIMRALKAAS KDDSIITVLT GNGDYYSSGN DLTNFTDIPP GGVEEKAKNN AVLLREFVGC FIDFPKPLIA VVNGPAVGIS VTLLGLFDAV YASDRATFHT PFSHLGQSPE GCSSYTFPKI MSPAKATEML IFGKKLTAGE ACAQGLVTEV FPDSTFQKEV WTRLKAFAKL PPNALRISKE VIRKREREKL HAVNAEECNV LQGRWLSDEC TNAVVNFLSR KSKL. It is sometimes possible for the material contained within the vial of "Peroxisomal D3,D2-Enoyl-CoA Isomerase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
