Prostaglandin E Synthase 3 Recombinant Protein | PTGES3 recombinant protein
Recombinant Human Prostaglandin E Synthase 3
Gene Names
PTGES3; P23; TEBP; cPGES
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Prostaglandin E Synthase 3; Recombinant Human Prostaglandin E Synthase 3; PTGES3 Human; Prostaglandin E Synthase 3 Human Recombinant; TEBP; CPGES; SID3177; 5730442A20Rik; p23; HSP90 co-chaperone; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; Telomerase-binding protein p23; Progesterone receptor complex p23; PTGES3; PTGES3 recombinant protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The PTGES3 protein solution contains 20mM Tris-HCl, pH-8, 1mM DTT & 10% Glycerol.
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE
Sequence Length
139
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Related Product Information for PTGES3 recombinant protein
Description: Recombinant Human PTGES3 produced in E Coli is a single,non-glycosylated polypeptide chain containing 160 amino acids (1-160 a.a.) and having a molecular mass of 18.6 kDa.PTGES3 is purified by convential chromatogrpahy techniques.
Introduction: PTGES3 takes part as a cochaperone and is involved in signal transduction. PTGES3 is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexess. PTGES3 is necessary for appropriate functioning of the glucocorticoid and other steroid receptors.PTGES3 localizes to genomic response elements in a hormone-dependent method and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
Introduction: PTGES3 takes part as a cochaperone and is involved in signal transduction. PTGES3 is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexess. PTGES3 is necessary for appropriate functioning of the glucocorticoid and other steroid receptors.PTGES3 localizes to genomic response elements in a hormone-dependent method and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,476 Da
NCBI Official Full Name
prostaglandin E synthase 3 isoform b
NCBI Official Synonym Full Names
prostaglandin E synthase 3 (cytosolic)
NCBI Official Symbol
PTGES3
NCBI Official Synonym Symbols
P23; TEBP; cPGES
NCBI Protein Information
prostaglandin E synthase 3; Hsp90 co-chaperone; cytosolic prostaglandin E synthase; cytosolic prostaglandin E2 synthase; progesterone receptor complex p23; telomerase-binding protein p23; unactive progesterone receptor, 23 kD
UniProt Protein Name
Prostaglandin E synthase 3
Protein Family
UniProt Gene Name
PTGES3
UniProt Synonym Gene Names
P23; TEBP; cPGES
UniProt Entry Name
TEBP_HUMAN
Uniprot Description
TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.
Protein type: EC 5.3.99.3; Nuclear receptor co-regulator; Chaperone; Transferase; Isomerase
Chromosomal Location of Human Ortholog: 12q13.3|12
Cellular Component: nucleoplasm; chromosome, telomeric region; cytoplasm; telomerase holoenzyme complex; cytosol; nucleus
Molecular Function: telomerase activity; protein binding; unfolded protein binding; prostaglandin-E synthase activity
Biological Process: RNA-dependent DNA replication; cyclooxygenase pathway; arachidonic acid metabolic process; signal transduction; prostaglandin biosynthetic process; telomere maintenance
Research Articles on PTGES3
1. FKBP4, p23, and Aha1 cooperatively regulate the progression of hAgo2 through the chaperone cycle.
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Product Notes
The PTGES3 ptges3 (Catalog #AAA143873) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE. It is sometimes possible for the material contained within the vial of "Prostaglandin E Synthase 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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