Complement C1q Tumor Necrosis Factor-Related Protein 3 Recombinant Protein | C1QTNF3 recombinant protein
Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 3
Gene Names
C1QTNF3; CORS; CORCS; CTRP3; CORS26; C1ATNF3; CORS-26
Purity
The purity of C1QTNF3 is greater than 95% as determined by SDS PAGE.
Synonyms
Complement C1q Tumor Necrosis Factor-Related Protein 3; Recombinant Human Complement C1q Tumor Necrosis Factor-Related Protein 3; C1QTNF3 Human; Complement C1q Tumor Necrosis Factor-Related Protein 3 Human Recombinant; Complement C1q tumor necrosis factor-related protein 3; Secretory protein CORS26; C1QTNF3; CTRP3; Cors; Corcs; CORS26; FLJ37576; Cartducin; C1QTNF3 recombinant protein
Host
E Coli
Purity/Purification
The purity of C1QTNF3 is greater than 95% as determined by SDS PAGE.
Form/Format
Human C1QTNF3 was filtered (0.4 um) and lyophilized in 0.5 mg/ml in 0.05M Acetate buffer pH4.
Sequence
MKHHHHHHAS QDEYMESPQT GGLPPDCSKC CHGDYSFRGY QGPPGPPGPP GIPGNHGNNG NNGATGHEGA KGEKGDKGDL GPRGERGQHG PKGEKGYPGI PPELQIAFMA SLATHFSNQN SGIIFSSVET NIGNFFDVMT GRFGAPVSGV YFFTFSMMKH EDVEEVYVYL MHNGNTVFSM YSYEMKGKSD TSSNHAVLKL AKGDEVWLRM GNGALHGDHQ RFSTFAGFLLFETK
Sequence Length
246
Solubility
It is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10 ug/ml. In higher concentrations the solubility of the protein is limited. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell culture.
Preparation and Storage
Store lyophilized C1QTNF3 at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
Related Product Information for C1QTNF3 recombinant protein
Description: C1QTNF3 Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 234 amino acids and having a molecular mass of 25.4 kDa. The protein contains an extra 10 aa His tag at N-terminus. The C1QTNF3 amino acid sequence is identical to UniProtKB/Swiss-Prot entry Q9BXJ4 amino acids 23246. The C1QTNF3 is purified by proprietary chromatographic techniques.
Introduction: C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.
Introduction: C1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.
Product Categories/Family for C1QTNF3 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
35,183 Da
NCBI Official Full Name
complement C1q tumor necrosis factor-related protein 3 isoform a
NCBI Official Synonym Full Names
C1q and tumor necrosis factor related protein 3
NCBI Official Symbol
C1QTNF3
NCBI Official Synonym Symbols
CORS; CORCS; CTRP3; CORS26; C1ATNF3; CORS-26
NCBI Protein Information
complement C1q tumor necrosis factor-related protein 3; cartonectin; collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; secretory protein CORS26
UniProt Protein Name
Complement C1q tumor necrosis factor-related protein 3
Protein Family
UniProt Gene Name
C1QTNF3
UniProt Synonym Gene Names
CTRP3; CORS26
UniProt Entry Name
C1QT3_HUMAN
Uniprot Description
C1QTNF3: 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5p13
Cellular Component: extracellular space; collagen; membrane
Molecular Function: protein binding
Biological Process: fat cell differentiation; negative regulation of inflammatory response; negative regulation of gluconeogenesis; negative regulation of NF-kappaB import into nucleus; positive regulation of cytokine secretion
Research Articles on C1QTNF3
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Product Notes
The C1QTNF3 c1qtnf3 (Catalog #AAA143414) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MKHHHHHHAS QDEYMESPQT GGLPPDCSKC CHGDYSFRGY QGPPGPPGPP GIPGNHGNNG NNGATGHEGA KGEKGDKGDL GPRGERGQHG PKGEKGYPGI PPELQIAFMA SLATHFSNQN SGIIFSSVET NIGNFFDVMT GRFGAPVSGV YFFTFSMMKH EDVEEVYVYL MHNGNTVFSM YSYEMKGKSD TSSNHAVLKL AKGDEVWLRM GNGALHGDHQ RFSTFAGFLL FETK. It is sometimes possible for the material contained within the vial of "Complement C1q Tumor Necrosis Factor-Related Protein 3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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