Transcription Elongation Factor A Recombinant Protein | TCEAL1 recombinant protein

Recombinant Human Transcription Elongation Factor A (SII)-Like 1

Cat. Num. AAA143060

• Gene Names: TCEAL1; p21; SIIR; WEX9; pp21
• Purity: Greater than 90.0% as determined by SDS-PAGE.
• Synonyms: Transcription Elongation Factor A; Recombinant Human Transcription Elongation Factor A (SII)-Like 1; TCEAL1 Human; Transcription Elongation Factor A (SII)-Like 1 Human Recombinant; Transcription elongation factor A protein-like 1; TCEA-like protein 1; Nuclear phosphoprotein p21/SIIR; Transcription elongation factor S-II protein-like 1; TCEAL1; SIIR; p21; pp21; TCEAL1 recombinant protein

• Host: E Coli
• Purity/Purification: Greater than 90.0% as determined by SDS-PAGE.
• Form/Format: The TCEAL1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 20% glycerol and 0.1M NaCl.; Sterile Filtered colorless solution.
• Sequence: MDKPRKENEE EPQSAPKTDE ERPPVEHSPE KQSPEEQSSE EQSSEEEFFP EELLPELLPE MLLSEERPPQ EGLSRKDLFE GRPPMEQPPC GVGKHKLEEG SFKERLARSR PQFRGDIHGR NLSNEEMIQA ADELEEMKRV RNKLMIMHWK AKRSRPYPIL EHHHHHH.
• Sequence Length: 159

• Preparation and Storage: Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.

Related Product Information for TCEAL1 recombinant protein

Description: TCEAL1 Human Recombinant fused with an 8 amino acid His tag at C-terminus produced in E Coli is a single, non-glycosylated, polypeptide chain containing 167 amino acids (1-159 a.a.) and having a molecular mass of 19.7kDa. The TCEAL1 is purified by proprietary chromatographic techniques.

Introduction: Transcription elongation factor A protein-like 1 (TCEAL1) is a member of the transcription elongation factor A (SII)-like (TCEAL) family, which may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. TCEAL1 is involved in transcriptional regulation. TCEAL1 is expressed in all tissues, especially highly expressed in the heart, ovary, prostate and skeletal muscle.

Product Categories/Family for TCEAL1 recombinant protein

Recombinant & Natural Proteins; Recombinant Proteins; Transcription Elongation Factor

NCBI and Uniprot Product Information

• NCBI GI #: 55749406
• NCBI GeneID: 9338
• NCBI Accession #: NP_001006640.1
• NCBI GenBank Nucleotide #: NM_001006639.1
• UniProt Accession #: Q15170; Q9UJQ9
• Molecular Weight: 18,641 Da
• NCBI Official Full Name: transcription elongation factor A protein-like 1
• NCBI Official Synonym Full Names: transcription elongation factor A (SII)-like 1
• NCBI Official Symbol: TCEAL1
• NCBI Official Synonym Symbols: p21; SIIR; WEX9; pp21
• NCBI Protein Information: transcription elongation factor A protein-like 1; TCEA-like protein 1; nuclear phosphoprotein p21/SIIR; transcription elongation factor S-II protein-like 1
• UniProt Protein Name: Transcription elongation factor A protein-like 1
• Protein Family: Transcription elongation factor A protein
• UniProt Gene Name: TCEAL1
• UniProt Synonym Gene Names: SIIR; TCEA-like protein 1
• UniProt Entry Name: TCAL1_HUMAN

NCBI Description

This gene encodes a member of the transcription elongation factor A (SII)-like (TCEAL) gene family. Members of this family may function as nuclear phosphoproteins that modulate transcription in a promoter context-dependent manner. The encoded protein is similar to transcription elongation factor A/transcription factor SII and contains a zinc finger-like motif as well as a sequence related to the transcription factor SII Pol II-binding region. It may exert its effects via protein-protein interactions with other transcriptional regulators rather than via direct binding of DNA. Multiple family members are located on the X chromosome. Alternative splicing results in multiple transcript variants encoding a single isoform. [provided by RefSeq, Jul 2008]

Uniprot Description

SIIR: May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context- dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly. Belongs to the TFS-II family. TFA subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription initiation complex

Chromosomal Location of Human Ortholog: Xq22.1

Cellular Component: nucleoplasm; nucleus

Molecular Function: transcription factor activity

Biological Process: transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter