8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase (TTHA1582) Recombinant Protein | TTHA1582 recombinant protein

Recombinant Thermus thermophilus 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase (TTHA1582)

Cat. Num. AAA1422552

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase (TTHA1582); Recombinant Thermus thermophilus 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase (TTHA1582); TTHA1582 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-395, Full length protein
• Sequence: MSLDLRARVREELERLKREGLYISPKVLEAPQEPVTRVEGREVVNLASNNYLGFANHPYLKEKARQYLEKWGAGSGAVRTIAGTFTYHVELEEALARFKGTESALVLQSGFTANQGVLGALLKEGDVVFSDELNHASIIDGLRLTKATRLVFRHADVAHLEELLKAHDTDGLKLIVTDGVFSMDGDIAPLDKIVPLAKKYKAVVYVDDAHGSGVLGEKGKGTVHHFGFHQDPDVVQVATLSKAWAGIGGYAAGARELKDLLINKARPFLFSTSHPPAVVGALLGALELIEKEPERVERLWENTRYFKRELARLGYDTLGSQTPITPVLFGEAPLAFEASRLLLEEGVFAVGIGFPTVPRGKARIRNIVTAAHTKEMLDKALEAYEKVGKRLGIIR
• Sequence Length: 395

• Species: Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 499548002
• NCBI Accession #: WP_011228785.1
• NCBI GenBank Nucleotide #: WP_011228785.1
• UniProt Accession #: Q5SHZ8
• Molecular Weight: 43,362 Da
• NCBI Official Full Name: 8-amino-7-oxononanoate synthase
• UniProt Protein Name: 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase
• Protein Family: 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase
• UniProt Gene Name: TTHA1582
• UniProt Synonym Gene Names: AONS/AKB ligase; 7-KAP synthase; KAPA synthase

Uniprot Description

Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. It also converts 2-amino-3-ketobutyrate and CoA to glycine and acetyl-CoA. Activity is also observed with the following combinations of substrates: acetyl-CoA and either L-alanine or L-serine, pimeloyl-CoA and either glycine or L-serine, and palmitoyl-CoA with L-alanine.