Clumping factor A (clfA) Recombinant Protein | clfA recombinant protein
Recombinant Staphylococcus aureus Clumping factor A (clfA), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Clumping factor A (clfA); Recombinant Staphylococcus aureus Clumping factor A (clfA); partial; clfA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
229-559 Partial.
Sequence
GTDITNQLTDVKVTIDSGTTVYPHQAGYVKLNYGFSVPNSAVKGDTFKITVPKELNLNGVTSTAKVPPIMAGDQVLANGVIDSDGNVIYTFTDYVDNKENVTANITMPAYIDPENVTKTGNVTLTTGIGTNTASKTVLIDYEKYGQFHNLSIKGTIDQIDKTNNTYRQTIYVNPSGDNVVLPALTGNLIPNTKSNALIDAKNTDIKVYRVDNANDLSESYYVNPSDFEDVTNQVRISFPNANQYKVEFPTDDDQITTPYIVVVNGHIDPASTGDLALRSTFYGYDSNFIWRSMSWDNEVAFNNGSGSGDGIDKPVVPEQPDEPGEIEPIPE
Sequence Length
559
Species
Staphylococcus aureus (strain N315)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
102,409 Da
NCBI Official Full Name
clumping factor A
UniProt Protein Name
Clumping factor A
Protein Family
UniProt Gene Name
clfA
Uniprot Description
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps, which diminish the ability of group IIA phospholipase A2 to cause bacterial phospholipid hydrolysis and killing. Significantly decreases macrophage phagocytosis possibly thanks to the clumps, clumped bacteria being too large to be phagocytosed. Dominant factor responsible for human platelet aggregation, which may be an important mechanism for initiating infective endocarditis ().
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Product Notes
The clfA clfa (Catalog #AAA1418890) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 229-559 Partial. The amino acid sequence is listed below: GTDITNQLTD VKVTIDSGTT VYPHQAGYVK LNYGFSVPNS AVKGDTFKIT VPKELNLNGV TSTAKVPPIM AGDQVLANGV IDSDGNVIYT FTDYVDNKEN VTANITMPAY IDPENVTKTG NVTLTTGIGT NTASKTVLID YEKYGQFHNL SIKGTIDQID KTNNTYRQTI YVNPSGDNVV LPALTGNLIP NTKSNALIDA KNTDIKVYRV DNANDLSESY YVNPSDFEDV TNQVRISFPN ANQYKVEFPT DDDQITTPYI VVVNGHIDPA STGDLALRST FYGYDSNFIW RSMSWDNEVA FNNGSGSGDG IDKPVVPEQP DEPGEIEPIP E . It is sometimes possible for the material contained within the vial of "Clumping factor A (clfA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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