Hamster Erythrocyte Membrane Protein ELISA Kit | EMP elisa kit
Hamster Erythrocyte Membrane Protein ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Epb4.2: Probably plays an important role in the regulation of erythrocyte shape and mechanical properties. Defects in EPB42 are the cause of spherocytosis type 5 (SPH5); also known as hereditary spherocytosis type 5 (HS5). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Absence of band 4.2 associated with spur or target erythrocytes has also been reported. Belongs to the transglutaminase superfamily. Transglutaminase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 15q15-q21
Cellular Component: cortical cytoskeleton; cytoskeleton; plasma membrane
Molecular Function: protein binding; structural constituent of cytoskeleton; protein-glutamine gamma-glutamyltransferase activity; ATP binding
Biological Process: spleen development; regulation of cell shape; iron ion homeostasis; erythrocyte maturation; hemoglobin metabolic process; cell morphogenesis; peptide cross-linking
Disease: Spherocytosis, Type 5
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Product Notes
The Hamster EMP (Catalog #AAA014169) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA014169 ELISA Kit recognizes Hamster EMP. It is sometimes possible for the material contained within the vial of "Erythrocyte Membrane Protein, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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