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Growth and Differentiation factor 11 Recombinant Protein | GDF11 recombinant protein

Recombinant Human Growth and Differentiation factor 11, His Tag

Gene Names
GDF11; BMP11; BMP-11
Purity
Greater than 85.0% as determined by SDS-PAGE.
Synonyms
Growth and Differentiation factor 11; Recombinant Human Growth and Differentiation factor 11; His Tag; GDF11 Human; His; Growth and Differentiation factor 11 Human Recombinant; Growth Differentiation Factor 11; BMP11; Bone Morphogenetic Protein 11; BMP-11; GDF-11; Growth/Differentiation Factor 11; Growth/differentiation factor 11; GDF11 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 85.0% as determined by SDS-PAGE.
Form/Format
GDF11 protein solution (1mg/ml) containing 20mM Tris-HCl (pH8.0) and 10% glycerol.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHHSSGLVPRGSH MGSNLGLDCDEHSSESRCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGQC EYMFMQKYPH THLVQQANPR GSAGPCCTPTKMSPINMLYF NDKQQIIYGK IPGMVVDRCG CS
Sequence Length
407
Related Product Information for GDF11 recombinant protein
Introduction: GDF-11 belongs to the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. GDF-11 is a central developmental factor which controls muscular and neural development. In adults, GDF-11 encourages cardiac hypertrophy reverse by the revival of cardiomyocytes.

Description: GDF11 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids (299-407a.a) and having a molecular mass of 14.8kDa. GDF11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for GDF11 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
45,091 Da
NCBI Official Full Name
growth/differentiation factor 11
NCBI Official Synonym Full Names
growth differentiation factor 11
NCBI Official Symbol
GDF11
NCBI Official Synonym Symbols
BMP11; BMP-11
NCBI Protein Information
growth/differentiation factor 11
UniProt Protein Name
Growth/differentiation factor 11
UniProt Gene Name
GDF11
UniProt Synonym Gene Names
BMP11; GDF-11; BMP-11
UniProt Entry Name
GDF11_HUMAN

Uniprot Description

GDF11: Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: extracellular space; intracellular membrane-bound organelle; nucleoplasm; protein complex

Molecular Function: cytokine activity; transforming growth factor beta receptor binding

Biological Process: cell development; mesoderm development; nervous system development; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development

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Product Notes

The GDF11 gdf11 (Catalog #AAA141087) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHHSSGLVPR GSH MGSNLG LDCDEHSSES RCCR YPLTVDFEAF GWDWIIAPKR YKANYCSGQC EYMFMQKYPH THLVQQANPR GSAGPCCTPT KMSPINMLYF NDKQQIIYGK IPGMVVDRCG CS. It is sometimes possible for the material contained within the vial of "Growth and Differentiation factor 11, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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