Tumor necrosis factor receptor superfamily member 1B (Tnfrsf1b) Recombinant Protein | Tnfrsf1b recombinant protein
Recombinant Rat Tumor necrosis factor receptor superfamily member 1B (Tnfrsf1b), partial
Gene Names
Tnfrsf1b; Tnfr2
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Tumor necrosis factor receptor superfamily member 1B (Tnfrsf1b); Recombinant Rat Tumor necrosis factor receptor superfamily member 1B (Tnfrsf1b); partial; Tnfrsf1b recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
23-258
Sequence
VPAKVVLT PYKPEPGNQC QISQEYYDKK AQMCCAKCPP GQYAKHFCNK TSDTVCADCA AGMFTQVWNH LHTCLSCSSS CSDDQVETHN CTKKQNRVCA CNADSYCALK LHSGNCRQCM KLSKCGPGFG VARSRTSNGN VICSACAPGT FSDTTSSTDV CRPHRICSIL AIPGNASTDA VCASESPTPS AVPRTIYVSQ PEPTRSQPMD QEPGPSQTPH IPVSLGSTPI IEPSITGG
Sequence Length
236
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Tnfrsf1b recombinant protein
This protein is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
50,148 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 1B
NCBI Official Synonym Full Names
TNF receptor superfamily member 1B
NCBI Official Symbol
Tnfrsf1b
NCBI Official Synonym Symbols
Tnfr2
NCBI Protein Information
tumor necrosis factor receptor superfamily member 1B
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 1B
Protein Family
UniProt Gene Name
Tnfrsf1b
UniProt Synonym Gene Names
Tnfr2; TNF-R2; TNF-RII; TNFR-II
NCBI Description
mediates brain uptake of tumor necrosis factor (TNF)-alpha from the circulation [RGD, Feb 2006]
Uniprot Description
Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2 ().
Research Articles on Tnfrsf1b
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Product Notes
The Tnfrsf1b tnfrsf1b (Catalog #AAA1410630) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 23-258. The amino acid sequence is listed below: VPAKVVLT PYKPEPGNQC QISQEYYDKK AQMCCAKCPP GQYAKHFCNK TSDTVCADCA AGMFTQVWNH LHTCLSCSSS CSDDQVETHN CTKKQNRVCA CNADSYCALK LHSGNCRQCM KLSKCGPGFG VARSRTSNGN VICSACAPGT FSDTTSSTDV CRPHRICSIL AIPGNASTDA VCASESPTPS AVPRTIYVSQ PEPTRSQPMD QEPGPSQTPH IPVSLGSTPI IEPSITGG. It is sometimes possible for the material contained within the vial of "Tumor necrosis factor receptor superfamily member 1B (Tnfrsf1b), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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