Bone Morphogenetic protein-3 Active Protein | BMP3 active protein
Recombinant Human Bone Morphogenetic protein-3
Gene Names
BMP3; BMP-3A
Purity
Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Bone Morphogenetic protein-3; Recombinant Human Bone Morphogenetic protein-3; BMP3 Human; Bone Morphogenetic protein-3 Human Recombinant; Bone Morphogenetic Protein 3; Osteogenin; Bone Morphogenetic Protein 3 (Osteogenic); Bone Morphogenetic Protein 3A; BMP-3A; BMP-3; Bone Morphogenetic Protein-3; BMP3A; BMP3; BMP3 active protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by HPLC. (b) Analysis by SDS-PAGE.
Form/Format
BMP-3 protein was lyophilized from a 0.2 um filtered concentrated solution in 30% Acetonitrile and 0.1% TFA.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
QWIEPRNCAR RYLKVDFADI GWSEWIISPK SFDAYYCSGA CQFPMPKSLK PSNHATIQSI VRAVGVVPGI PEPCCVPEKM SSLSILFFDE NKNVVLKVYP NMTVESCACR
Sequence Length
472
Biological Activity
The ED50 as determined by its ability to inhibit BMP-2-induced activity in murine MC3T3- E1 cells.
Preparation and Storage
Lyophilized BMP3 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution BMP-3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Related Product Information for BMP3 active protein
Introduction: Bone Morphogenetic Protein 3 (BMP3) is one of the BMPs, some of which are members of the TGF-beta superfamily (BMP2-7). There are more than 13 BMPs, which are involved in inducing cartilage and bone formation, embryogenesis and morphogenesis of various tissues and organs. In addition, BMPs regulate the growth, differentiation, chemotaxis, and apoptosis of various cell types. Akin to most other TGF-beta family proteins, BMPs are extremely conserved across animal species. At the amino acid sequence level, mature human and rat BMP3 are 98% identical.
Description: BMP3 Human Recombinant produced in E Coli is a non-glycosylated disulfide linked homodimer containing 2 chains of 110 amino acids and having a molecular mass of 24.8kDa.The BMP-3 is purified by proprietary chromatographic techniques.
Description: BMP3 Human Recombinant produced in E Coli is a non-glycosylated disulfide linked homodimer containing 2 chains of 110 amino acids and having a molecular mass of 24.8kDa.The BMP-3 is purified by proprietary chromatographic techniques.
Product Categories/Family for BMP3 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
53,372 Da
NCBI Official Full Name
bone morphogenetic protein 3 preproprotein
NCBI Official Synonym Full Names
bone morphogenetic protein 3
NCBI Official Symbol
BMP3
NCBI Official Synonym Symbols
BMP-3A
NCBI Protein Information
bone morphogenetic protein 3
UniProt Protein Name
Bone morphogenetic protein 3
Protein Family
UniProt Gene Name
BMP3
UniProt Synonym Gene Names
BMP3A; BMP-3; BMP-3A
UniProt Entry Name
BMP3_HUMAN
Uniprot Description
BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family.
Protein type: Cytokine; Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 4q21
Cellular Component: extracellular space
Molecular Function: cytokine activity; receptor binding; transforming growth factor beta receptor binding
Biological Process: BMP signaling pathway; cell development; cell-cell signaling; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development
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Product Notes
The BMP3 bmp3 (Catalog #AAA140880) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: QWIEPRNCAR RYLKVDFADI GWSEWIISPK SFDAYYCSGA CQFPMPKSLK PSNHATIQSI VRAVGVVPGI PEPCCVPEKM SSLSILFFDE NKNVVLKVYP NMTVESCACR. It is sometimes possible for the material contained within the vial of "Bone Morphogenetic protein-3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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