Myxovirus Resistance 1 Recombinant Protein | MX1 recombinant protein
Recombinant Human Myxovirus Resistance 1
Gene Names
MX1; MX; MxA; IFI78; IFI-78K
Purity
Greater than 85% as determined by SDS-PAGE.
Synonyms
Myxovirus Resistance 1; Recombinant Human Myxovirus Resistance 1; MX1 Human; Myxovirus Resistance 1 Human Recombinant; MX Dynamin-Like GTPase 1; Interferon-Regulated Resistance GTP-Binding Protein MxA; Interferon-Inducible Protein P78; Interferon-Induced Protein P78; Myxoma Resistance Protein 1; IFI-78K; IFI78; MX; Myxovirus (Influenza) Resistance 1; Homolog Of Murine (Interferon-Inducible Protein P78); Myxovirus (Influenza Virus) Resistance 1; Interferon-Inducible Protein P78 (Mouse); Interferon-Induced GTP-Binding Protein Mx1; Myxovirus Resistance Protein 1; MxA; Interferon-induced GTP-binding protein Mx1; MX1 recombinant protein
Host
E Coli
Purity/Purification
Greater than 85% as determined by SDS-PAGE.
Form/Format
MX1 protein solution (0.25mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMVVSEVD IAKADPAAAS HPLLLNGDAT VAQKNPGSVA ENNLCSQYEEKVRPCIDLID SLRALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL VLKLKKLVNEDKWRGKVSYQ DYEIEISDAS EVEKEINKAQ NAIAGEGMGISHELITLEIS SRDVPDLTLI DLPGITRVAV GNQPADIGYK IKTLIKKYIQRQETISLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDKGTE DKVVDVVRNL VFHLKKGYMIVKCRGQQEIQ DQLSLSEALQ REKIFFENHP YFRDLLEEGK ATVPCLAEKL TSELITHICKSLPLLENQIK ETHQRITEEL QKYGVDIPED ENEKMFFLID KVNAFNQDITALMQGEETVG EEDIRLFTRL RHEFHKWSTI IENNFQEGHK ILSRKIQKFE NQYRGRELPG FVNYRTFETIVKQQIKALEE PAVDMLHTVT DMVRLAFTDV SIKNFEEFFN LHRTAKSKIE DIRAEQEREGEKLIRLHFQM EQIVYCQDQV YRGALQKVRE KELEEEKKKK SWDFGAFQSSSATDSSMEEI FQHLMAYHQE ASKRISSHIP LIIQFFMLQT YGQQLQKAML QLLQDKDTYS WLLKERSDTSDKRKFLKERL ARLTQARRRL AQFPG
Sequence Length
662
Related Product Information for MX1 recombinant protein
Introduction: Myxovirus Resistance 1, also known as MX1 is a guanosine triphosphate (GTP)-metabolizing protein which takes part in the cellular antiviral response. MX1 is induced by type I and type II interferons, and also antagonizes the replication process of some different RNA & DNA viruses. In addition, there is a related gene located adjacent to MX1 on chromosome 21, and there are multiple pseudogenes positioned in a cluster on chromosome 4.
Description: MX1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 685 amino acids (1-662 a.a) and having a molecular mass of 77.9kDa. MX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Description: MX1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 685 amino acids (1-662 a.a) and having a molecular mass of 77.9kDa. MX1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for MX1 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
55,661 Da
NCBI Official Full Name
interferon-induced GTP-binding protein Mx1 isoform a
NCBI Official Synonym Full Names
MX dynamin like GTPase 1
NCBI Official Symbol
MX1
NCBI Official Synonym Symbols
MX; MxA; IFI78; IFI-78K
NCBI Protein Information
interferon-induced GTP-binding protein Mx1
UniProt Protein Name
Interferon-induced GTP-binding protein Mx1
Protein Family
UniProt Gene Name
MX1
UniProt Synonym Gene Names
IFI-78K
UniProt Entry Name
MX1_HUMAN
Uniprot Description
MX1: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens. Shows activity against influenza viruses, rhabdovirus VSV, bunyavirus LACV, Thogoto virus, measles virus, Hantaan virus, Coxsackie virus CVB, Rift Valley fever virus RVFV, hepatitis B virus HBV, and Crimean- Congo hemorrhagic fever virus CCHFV. Belongs to the dynamin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Apoptosis; Hydrolase
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: cytoplasm; cytosol; nuclear membrane; nucleus; perinuclear region of cytoplasm
Molecular Function: GTPase activity; microtubule binding; protein binding
Biological Process: apoptosis; defense response; defense response to virus; innate immune response; negative regulation of viral genome replication; organelle fission; response to virus; signal transduction
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Product Notes
The MX1 mx1 (Catalog #AAA140625) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMVV SEVD IAKADPAAAS HPLLLNGDAT VAQKNPGSVA ENNLCSQYEE KVRPCIDLID SLRALGVEQD LALPAIAVIG DQSSGKSSVL EALSGVALPR GSGIVTRCPL VLKLKKLVNE DKWRGKVSYQ DYEIEISDAS EVEKEINKAQ NAIAGEGMGI SHELITLEIS SRDVPDLTLI DLPGITRVAV GNQPADIGYK IKTLIKKYIQ RQETISLVVV PSNVDIATTE ALSMAQEVDP EGDRTIGILT KPDLVDKGTE DKVVDVVRNL VFHLKKGYMI VKCRGQQEIQ DQLSLSEALQ REKIFFENHP YFRDLLEEGK ATVPCLAEKL TSELITHICK SLPLLENQIK ETHQRITEEL QKYGVDIPED ENEKMFFLID KVNAFNQDIT ALMQGEETVG EEDIRLFTRL RHEFHKWSTI IENNFQEGHK ILSRKIQKFE NQYRGRELPG FVNYRTFETI VKQQIKALEE PAVDMLHTVT DMVRLAFTDV SIKNFEEFFN LHRTAKSKIE DIRAEQEREG EKLIRLHFQM EQIVYCQDQV YRGALQKVRE KELEEEKKKK SWDFGAFQSS SATDSSMEEI FQHLMAYHQE ASKRISSHIP LIIQFFMLQT YGQQLQKAML QLLQDKDTYS WLLKERSDTS DKRKFLKERL ARLTQARRRL AQFPG. It is sometimes possible for the material contained within the vial of "Myxovirus Resistance 1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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