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Serine protease harobin Recombinant Protein | SVSP recombinant protein

Recombinant Lapemis hardwickii Serine protease harobin

Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Serine protease harobin; Recombinant Lapemis hardwickii Serine protease harobin; SVSP recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
34-265, Full length protein
Sequence
IIGGFECNPSEHRSLVYLYNSAGFFCSGTLLNHEWVLTAAHCNREDIQIRLGVHNVHVHYEDEQIRVPKEKLCCLSTNNCTQFSQDIMLIRLNSPVNYSEHIAPLSLPSNPPSMGSVCCVMGWGTITSPEVTYPEVPHCVDINILHIPVCQAAYPTMSGKNILCAGILEGGKDSCKGDSGGPLICNGQIQGIVSWGRFPCAQFLEPGIYTKVFDYKDWIEGIIAGNSNVICP
Sequence Length
232
Species
Lapemis hardwickii (Hardwick's sea snake)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
UniProt Accession #
Molecular Weight
28,996 Da
NCBI Official Full Name
Serine protease harobin
UniProt Protein Name
Serine protease harobin
Protein Family
UniProt Gene Name
SVSP
UniProt Synonym Gene Names
SVSP

Uniprot Description

Serine protein with fibrinolytic and fibrinogenolytic activities. Degrades Bbeta-chain (FGB) of fibrinogen first and then the Aalpha-chain (FGA). Gamma-chain (FGG) are also digested on prolonged incubation. In vitro, it cleaves high molecular weight (HMW) kininogen (KNG) releasing bradykinin that promotes vasodilation. In vitro and in vivo, it cleaves angiotensin-2 (AGT). This explains the reduction of blood pressure in hypertensive rats. Has also antithrombotic effects on thrombosis animal models.

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Product Notes

The Serine protease harobin svsp (Catalog #AAA1404986) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 34-265, Full length protein. The amino acid sequence is listed below: IIGGFECNPS EHRSLVYLYN SAGFFCSGTL LNHEWVLTAA HCNREDIQIR LGVHNVHVHY EDEQIRVPKE KLCCLSTNNC TQFSQDIMLI RLNSPVNYSE HIAPLSLPSN PPSMGSVCCV MGWGTITSPE VTYPEVPHCV DINILHIPVC QAAYPTMSGK NILCAGILEG GKDSCKGDSG GPLICNGQIQ GIVSWGRFPC AQFLEPGIYT KVFDYKDWIE GIIAGNSNVI CP. It is sometimes possible for the material contained within the vial of "Serine protease harobin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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