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Rat LY6G Biotin Monoclonal Antibody | anti-LY6G antibody

Rat Anti Mouse LY6G Biotin

Applications
Flow Cytometry, Functional Assay, Immunohistochemistry
Purity
Protein A column.
Synonyms
LY6G Biotin; Monoclonal Antibody; Rat Anti Mouse LY6G Biotin; LY6G Antibody; Biotin; LY6G; Rat Anti Mouse Antibody; Lymphocyte antigen 6G; Ly-6G; Ly-6G.1; Ly6g; Gr1; Gr-1; anti-LY6G antibody
Ordering
For Research Use Only!
Host
Rat
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
YRmLy-6G
Purity/Purification
Protein A column.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
111
Applicable Applications for anti-LY6G antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Cell Depletion
Reconstitution
Reconstitute with H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
Ly-6G-transfected cell line.
Antibody Properties
This antibody recognizes only Ly-6G which is expressed on most myeloid cells in the bone marrow and all peripheral granulocytes. For flow cytometry, use 10 ul/106 cells. Exact titer for cell depletion in vivo (cytotoxicity) should be determined by the investigator.
Available Conjugates
This antibody is also available unconjugated and conjugated to FITC.
Preparation and Storage
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Related Product Information for anti-LY6G antibody
Introduction: Myeloid differentiation antigen Gr1 (Ly6G) is a GPI-anchored protein, which is briefly expressed on monocytes in the bone marrow. The level of the Ly6G expression in the bone marrow completely correlates with granulocyte differentiation and maturation. Ly6G ligation on murine neutrophils inhibits neutrophil recruitment, thus providing the first evidence of a function for the Ly6G molecule. Ly6G is seen primarily on neutrophils, also in a subgroup of eosinophils, differentiating pre-monocytes and plasmacytoid dendritic cells.
Product Categories/Family for anti-LY6G antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
11,798 Da
NCBI Official Full Name
Lymphocyte antigen 6G
UniProt Protein Name
Lymphocyte antigen 6G
Protein Family
UniProt Gene Name
Ly6g
UniProt Synonym Gene Names
Ly-6G
UniProt Entry Name
LY6G_MOUSE

Uniprot Description

Ly6g:

Cellular Component: membrane; plasma membrane; external side of plasma membrane

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Product Notes

The LY6G ly6g (Catalog #AAA140390) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's LY6G Biotin can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunohistochemistry (IHC), Cell Depletion. Researchers should empirically determine the suitability of the LY6G ly6g for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "LY6G Biotin, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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