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Mouse Interleukin-2 Monoclonal Antibody | anti-IL-2 antibody

Mouse Anti Human Interleukin-2

Reactivity
A certain degree of functional cross reactivity with murine IL-2 was reported by some investigators.
Applications
ELISA, Western Blot, Immunoprecipitation, Immunohistochemistry
Purity
Ion Exchange.
Synonyms
Interleukin-2; Monoclonal Antibody; Mouse Anti Human Interleukin-2; IL 2 Antibody; Mouse Anti-Human; T-cell growth factor (TCGF); Aldesleukin; Lymphokine; IL-2; anti-IL-2 antibody
Ordering
For Research Use Only!
Host
Mouse
Reactivity
A certain degree of functional cross reactivity with murine IL-2 was reported by some investigators.
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
YNRhIL2
Purity/Purification
Ion Exchange.
Concentration
1mg/ml in PBS (after reconstitution). (varies by lot)
Sequence Length
41
Applicable Applications for anti-IL-2 antibody
ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Blocking T Cell Poroliferation
Application Notes
Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry, blocking T cell poroliferation.
Titer By direct ELISA
1:10,000 dilution will yield 0.4 O.D using alkaline phosphatase conjugated rabbit anti-mouse Ig (Jackson Laboratories). 1:50 dilution will block 70-80% of CTLL proliferative response to 50 units of r.human IL-2.
Reconstitution
Reconstitute with sterile H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Immunogen
r.Human IL-2.
Preparation and Storage
In lyophilized form, for long periods, store at 4 degree C in a dry environment. After reconstitution, if not intended for use within a month, aliquot and store at -20 degree C.
Antibody is shipped lyophilized at ambient temperature.
Related Product Information for anti-IL-2 antibody
Introduction: IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
Product Categories/Family for anti-IL-2 antibody

NCBI and Uniprot Product Information

NCBI GI #
Molecular Weight
4,762 Da
NCBI Official Full Name
IL-2, partial
UniProt Protein Name
IL-2 protein
Protein Family
UniProt Gene Name
IL-2
UniProt Entry Name
O95974_HUMAN

NCBI Description

The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. [provided by RefSeq, Jul 2008]

Similar Products

Product Notes

The IL-2 il-2 (Catalog #AAA140003) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Human Interleukin-2 reacts with A certain degree of functional cross reactivity with murine IL-2 was reported by some investigators. and may cross-react with other species as described in the data sheet. AAA Biotech's Interleukin-2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Blocking T Cell Poroliferation. Direct ELISA, Western Blot, Immunoprecipitation, immunohistochemistry, blocking T cell poroliferation. Researchers should empirically determine the suitability of the IL-2 il-2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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