NCBI Description
Non-catalytic subunit of Nuclear DNA-dependent RNA polymerase V; homologous to budding yeast RPB3 and the E. coli RNA polymerase alpha subunit. A closely related paralog, At2g15430 can substitute for At2g15400 in the context of Pol V and encodes the equivalent subunit of Pol II and Pol IV.
Uniprot Description
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerases IV and V which mediate short-interfering RNAs (siRNA) accumulation and subsequent RNA-directed DNA methylation-dependent (RdDM) transcriptional gene silencing (TGS) of endogenous repeated sequences, including transposable elements.
Product Notes
The RPB36B nrpd3b (Catalog #
AAA1390561) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-319, Full length protein. The amino acid sequence is listed below: MDGVTYQRFP TVKIRELKDD YAKFELRETD VSMANALRRV MISEVPTMAI HLVKIEVNSS VLNDEFIAQR LSLIPLTSER AMSMRFCQDC EDCNGDEHCE FCSVEFPLSA KCVTDQTLDV TSRDLYSADP TVTPVDFTSN SSTSDSSEHK GIIIAKLRRG QELKLKALAR KGIGKDHAKW SPAATVTYMY EPDIIINEEM MNTLTDEEKI DLIESSPTKV FGIDPVTGQV VVVDPEAYTY DEEVIKKAEA MGKPGLIEIH PKHDSFVFTV ESTGALKASQ LVLNAIDILK QKLDAIRLSD NTVEADDQFG ELGAHMREG.
It is sometimes possible for the material contained within the vial of
"DNA-directed RNA polymerase II subunit RPB3-B (RPB36B), Recombinant Protein" to become dispersed throughout the inside of
the vial, particularly around the seal of said vial, during shipment and storage. We always
suggest centrifuging these vials
to consolidate all of the liquid away from the lid and to the bottom of the vial prior to
opening. Please be advised that
certain products may require dry ice for shipping and that, if this is the case, an
additional dry ice fee may also be
required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are
absolutely not suitable for use in any
sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a
product from AAA Biotech, you
are explicitly certifying that said products will be properly tested and used in line with
industry standard. AAA Biotech
and its authorized distribution partners reserve the right to refuse to fulfill any order if
we have any indication that a
purchaser may be intending to use a product outside of our accepted criteria.
Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech
cannot be held
responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any
aspect of this datasheet at
any time and without notice. It is the responsibility of the customer to inform AAA Biotech
of any product performance
issues observed or experienced within 30 days of receipt of said product. To see additional
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