Envelope glycoprotein (GP), partial Recombinant Protein | GP recombinant protein
Recombinant Lake Victoria marburgvirus Envelope glycoprotein (GP), partial
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Envelope glycoprotein (GP); partial; Recombinant Lake Victoria marburgvirus Envelope glycoprotein (GP); Envelope glycoprotein; GP1; 2; GP; Virion spike glycoproteinCleaved into the following 2 chains:; 1. GP1; 2. GP2; GP recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
33-435. Partial, provide the GP1 chain.
Sequence
VDSVCSGTLQKTEDVHLMGFTLSGQKVADSPLEASKRWAFRTGVPPKNVEYTEGEEAKTCYNISVTDPSGKSLLLDPPTNVRDYPKCKTIHHIQGQNPHAQGIALHLWGAFFLYDRIASTTMYRGKVFTEGNIAAMIVNKTVHKMIFSRQGQGYRHMNLTSTNKYWTSSNGTQTNDTGCFGTLHEYNSTKNQTCAPSKTPPPPPTARPEIKPTSTPTDATRLNTTNPNSDDEDLTTSGSGSGEQELYTTSDAVTKQGLSSTMPPTPSPQPGTPQQGGNNTNHSQDATTELDNTNTTAQPPTPSHNTTTISTNNTSKHNLSTLSAPPQNTTNPNTQSMATENEKTSAPPKATLPPTENPTTEKSTNNTKSPTTMEPNTTNGHFTSPSSTPNSTTQHLIYFRRKR
Sequence Length
435
Species
Lake Victoria marburgvirus (strain Ozolin-75) (MARV) (Marburg virus (strain South Africa/Ozolin/1975))
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
74,481 Da
NCBI Official Full Name
Envelope glycoprotein
UniProt Protein Name
Envelope glycoprotein
Protein Family
UniProt Gene Name
GP
UniProt Synonym Gene Names
GP
UniProt Entry Name
VGP_MABVO
Uniprot Description
GP1 is responsible for binding to the receptor(s) on target cells. Interacts with CD209/DC-SIGN and CLEC4M/DC-SIGNR which act as cofactors for virus entry into the host cell. Binding to CD209 and CLEC4M, which are respectively found on dendritic cells (DCs), and on endothelial cells of liver sinusoids and lymph node sinuses, facilitate infection of macrophages and endothelial cells. These interactions not only facilitate virus cell entry, but also allow capture of viral particles by DCs and subsequent transmission to susceptible cells without DCs infection (trans infection) ().
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Product Notes
The GP gp (Catalog #AAA1378939) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 33-435. Partial, provide the GP1 chain. The amino acid sequence is listed below: VDSVCSGTLQ KTEDVHLMGF TLSGQKVADS PLEASKRWAF RTGVPPKNVE YTEGEEAKTC YNISVTDPSG KSLLLDPPTN VRDYPKCKTI HHIQGQNPHA QGIALHLWGA FFLYDRIAST TMYRGKVFTE GNIAAMIVNK TVHKMIFSRQ GQGYRHMNLT STNKYWTSSN GTQTNDTGCF GTLHEYNSTK NQTCAPSKTP PPPPTARPEI KPTSTPTDAT RLNTTNPNSD DEDLTTSGSG SGEQELYTTS DAVTKQGLSS TMPPTPSPQP GTPQQGGNNT NHSQDATTEL DNTNTTAQPP TPSHNTTTIS TNNTSKHNLS TLSAPPQNTT NPNTQSMATE NEKTSAPPKA TLPPTENPTT EKSTNNTKSP TTMEPNTTNG HFTSPSSTPN STTQHLIYFR RKR . It is sometimes possible for the material contained within the vial of "Envelope glycoprotein (GP), partial, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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