Tyrosine-protein kinase Src42A (Src42A) Recombinant Protein | Src42A recombinant protein
Recombinant Drosophila melanogaster Tyrosine-protein kinase Src42A (Src42A), partial
Gene Names
Src42A; CG14471; CG44128; CG7873; Dm SRC41; DmelCG44128; DmHD-29; dSrc; Dsrc41; Dsrc42A; DSrc42A; dtk-5; dtk5; Dtk5; HD-29; l(2)k10108; SK2-4; src; Src; SRC 42A; Src41; src42; Src42; src42a; src42A; Src42a; SRC42A; Su(D-raf)1; Su(phl)1; Su(Raf)1; Su1; Tk5
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Tyrosine-protein kinase Src42A (Src42A); Recombinant Drosophila melanogaster Tyrosine-protein kinase Src42A (Src42A); partial; Src42A recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
248-504; Protein kinase domain
Sequence
LKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIKEDEYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFY
Sequence Length
504
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,069 Da
NCBI Official Full Name
Src oncogene at 42A, isoform A
NCBI Official Synonym Full Names
Src oncogene at 42A
NCBI Official Symbol
Src42A
NCBI Official Synonym Symbols
CG14471; CG44128; CG7873; Dm SRC41; DmelCG44128; DmHD-29; dSrc; Dsrc41; Dsrc42A; DSrc42A; dtk-5; dtk5; Dtk5; HD-29; l(2)k10108; SK2-4; src; Src; SRC 42A; Src41; src42; Src42; src42a; src42A; Src42a; SRC42A; Su(D-raf)1; Su(phl)1; Su(Raf)1; Su1; Tk5
NCBI Protein Information
CG44128 gene product from transcript CG44128-RA
UniProt Protein Name
Tyrosine-protein kinase Src42A
Protein Family
UniProt Gene Name
Src42A
UniProt Synonym Gene Names
Dsrc41
Uniprot Description
Required directly or indirectly for the phosphorylation of drpr which is necessary for the interaction of drpr with shark and subsequent glial phagocytic activity (PubMed:18432193). Together with drpr and shark, promotes the migration of macrophages to sites of wounding as part of a signaling cascade where Scr42a detects production of hydrogen peroxide at wound sites which triggers phosphorylation of drpr and subsequent recruitment and activation of shark (PubMed:26028435). Essential for correct eye morphogenesis (ommatidial R7 neuron formation) which requires the Ras1/MAPK signal transduction pathway (PubMed:8682295). May be involved in the regulation of cytoskeleton organization and cell-cell contacts in developing ommatidia (PubMed:8682295). During embryogenesis, involved in regulation of dorsal closure where it may have a role in activating the JNK pathway in leading edge cells during this process (PubMed:16831834).
Research Articles on Src42A
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Product Notes
The Src42A src42a (Catalog #AAA1377262) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 248-504; Protein kinase domain. The amino acid sequence is listed below: LKFVRKLGSG QFGDVWEGLW NNTTPVAIKT LKSGTMDPKD FLAEAQIMKK LRHTKLIQLY AVCTVEEPIY IITELMKHGS LLEYLQAIAG KGRSLKMQTL IDMAAQIAAG MAYLESQNYI HRDLAARNVL VGDGNIVKIA DFGLARLIKE DEYEARVGAR FPIKWTAPEA ANYSKFSIKS DVWSFGILLT ELVTYGRIPY PGMTNAEVLT QVEHGYRMPQ PPNCEPRLYE IMLECWHKDP MRRPTFETLQ WKLEDFY . It is sometimes possible for the material contained within the vial of "Tyrosine-protein kinase Src42A (Src42A), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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