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Probable ATP-dependent RNA helicase DDX23 (DDX23) Recombinant Protein | DDX23 recombinant protein

Recombinant Human Probable ATP-dependent RNA helicase DDX23 (DDX23) , partial

Gene Names
DDX23; prp28; PRPF28; U5-100K; SNRNP100; U5-100KD
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Probable ATP-dependent RNA helicase DDX23 (DDX23); Recombinant Human Probable ATP-dependent RNA helicase DDX23 (DDX23); partial; DDX23 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
338-820. Partial
Sequence
ARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQKVFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTKKRREETIFA
Sequence Length
820
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for DDX23 recombinant protein
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This protein is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,401 Da
NCBI Official Full Name
probable ATP-dependent RNA helicase DDX23
NCBI Official Synonym Full Names
DEAD-box helicase 23
NCBI Official Symbol
DDX23
NCBI Official Synonym Symbols
prp28; PRPF28; U5-100K; SNRNP100; U5-100KD
NCBI Protein Information
probable ATP-dependent RNA helicase DDX23
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX23
UniProt Gene Name
DDX23

NCBI Description

This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene is a component of the U5 snRNP complex; it may facilitate conformational changes in the spliceosome during nuclear pre-mRNA splicing. An alternatively spliced transcript variant has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

Involved in pre-mRNA splicing and its phosphorylated form (by SRPK2) is required for spliceosomal B complex formation.

Research Articles on DDX23

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Product Notes

The DDX23 ddx23 (Catalog #AAA1377233) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 338-820. Partial. The amino acid sequence is listed below: ARLRKLRKKE AKQRWDDRHW SQKKLDEMTD RDWRIFREDY SITTKGGKIP NPIRSWKDSS LPPHILEVID KCGYKEPTPI QRQAIPIGLQ NRDIIGVAET GSGKTAAFLI PLLVWITTLP KIDRIEESDQ GPYAIILAPT RELAQQIEEE TIKFGKPLGI RTVAVIGGIS REDQGFRLRM GCEIVIATPG RLIDVLENRY LVLSRCTYVV LDEADRMIDM GFEPDVQKIL EHMPVSNQKP DTDEAEDPEK MLANFESGKH KYRQTVMFTA TMPPAVERLA RSYLRRPAVV YIGSAGKPHE RVEQKVFLMS ESEKRKKLLA ILEQGFDPPI IIFVNQKKGC DVLAKSLEKM GYNACTLHGG KGQEQREFAL SNLKAGAKDI LVATDVAGRG IDIQDVSMVV NYDMAKNIED YIHRIGRTGR AGKSGVAITF LTKEDSAVFY ELKQAILESP VSSCPPELAN HPDAQHKPGT ILTKKRREET IFA . It is sometimes possible for the material contained within the vial of "Probable ATP-dependent RNA helicase DDX23 (DDX23), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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