E3 ubiquitin-protein ligase TRIM32 (TRIM32) Recombinant Protein | TRIM32 recombinant protein
Recombinant Human E3 ubiquitin-protein ligase TRIM32 (TRIM32)
Gene Names
TRIM32; HT2A; BBS11; TATIP; LGMD2H
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
E3 ubiquitin-protein ligase TRIM32 (TRIM32); Recombinant Human E3 ubiquitin-protein ligase TRIM32 (TRIM32); TRIM32 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-653, Full length protein
Sequence
AAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVRCPFCSKITRITSLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGLVLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDLQARYKAVLQEYGHEERRVQDELARSRKFFTGSLAEVEKSNSQVVEEQSYLLNIAEVQAVSRCDYFLAKIKQADVALLEETADEEEPELTASLPRELTLQDVELLKVGHVGPLQIGQAVKKPRTVNVEDSWAMEATASAASTSVTFREMDMSPEEVVASPRASPAKQRGPEAASNIQQCLFLKKMGAKGSTPGMFNLPVSLYVTSQGEVLVADRGNYRIQVFTRKGFLKEIRRSPSGIDSFVLSFLGADLPNLTPLSVAMNCQGLIGVTDSYDNSLKVYTLDGHCVACHRSQLSKPWGITALPSGQFVVTDVEGGKLWCFTVDRGSGVVKYSCLCSAVRPKFVTCDAEGTVYFTQGLGLNLENRQNEHHLEGGFSIGSVGPDGQLGRQISHFFSENEDFRCIAGMCVDARGDLIVADSSRKEILHFPKGGGYSVLIREGLTCPVGIALTPKGQLLVLDCWDHCIKIYSYHLRRYSTP
Sequence Length
652
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for TRIM32 recombinant protein
This protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
71,989 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase TRIM32
NCBI Official Synonym Full Names
tripartite motif containing 32
NCBI Official Symbol
TRIM32
NCBI Official Synonym Symbols
HT2A; BBS11; TATIP; LGMD2H
NCBI Protein Information
E3 ubiquitin-protein ligase TRIM32
UniProt Protein Name
E3 ubiquitin-protein ligase TRIM32
Protein Family
UniProt Gene Name
TRIM32
UniProt Synonym Gene Names
HT2A
NCBI Description
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. The protein has also been localized to the nucleus, where it interacts with the activation domain of the HIV-1 Tat protein. The Tat protein activates transcription of HIV-1 genes. [provided by RefSeq, Jul 2008]
Uniprot Description
Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1 (dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.
Research Articles on TRIM32
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Product Notes
The TRIM32 trim32 (Catalog #AAA1375338) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-653, Full length protein. The amino acid sequence is listed below: AAAAASHLNL DALREVLECP ICMESFTEEQ LRPKLLHCGH TICRQCLEKL LASSINGVRC PFCSKITRIT SLTQLTDNLT VLKIIDTAGL SEAVGLLMCR SCGRRLPRQF CRSCGLVLCE PCREADHQPP GHCTLPVKEA AEERRRDFGE KLTRLRELMG ELQRRKAALE GVSKDLQARY KAVLQEYGHE ERRVQDELAR SRKFFTGSLA EVEKSNSQVV EEQSYLLNIA EVQAVSRCDY FLAKIKQADV ALLEETADEE EPELTASLPR ELTLQDVELL KVGHVGPLQI GQAVKKPRTV NVEDSWAMEA TASAASTSVT FREMDMSPEE VVASPRASPA KQRGPEAASN IQQCLFLKKM GAKGSTPGMF NLPVSLYVTS QGEVLVADRG NYRIQVFTRK GFLKEIRRSP SGIDSFVLSF LGADLPNLTP LSVAMNCQGL IGVTDSYDNS LKVYTLDGHC VACHRSQLSK PWGITALPSG QFVVTDVEGG KLWCFTVDRG SGVVKYSCLC SAVRPKFVTC DAEGTVYFTQ GLGLNLENRQ NEHHLEGGFS IGSVGPDGQL GRQISHFFSE NEDFRCIAGM CVDARGDLIV ADSSRKEILH FPKGGGYSVL IREGLTCPVG IALTPKGQLL VLDCWDHCIK IYSYHLRRYS TP. It is sometimes possible for the material contained within the vial of "E3 ubiquitin-protein ligase TRIM32 (TRIM32), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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