Interleukin-23 receptor (Il23r) Recombinant Protein | Il23r recombinant protein

Recombinant Mouse Interleukin-23 receptor (Il23r), partial

Cat. Num. AAA1371075

• Gene Names: Il23r; IL-23R
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Interleukin-23 receptor (Il23r); Recombinant Mouse Interleukin-23 receptor (Il23r); partial; Il23r recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 24-374
• Sequence: GITSINC SGDMWVEPGE IFQMGMNVSI YCQEALKHCR PRNLYFYKNG FKEEFDITRI NRTTARIWYK GFSEPHAYMH CTAECPGHFQ ETLICGKDIS SGHPPDAPSN LTCVIYEYSG NMTCTWNTGK PTYIDTKYIV HVKSLETEEE QQYLASSYVK ISTDSLQGSR KYLVWVQAVN SLGMENSQQL HVHLDDIVIP SASIISRAET TNDTVPKTIV YWKSKTMIEK VFCEMRYKTT TNQTWSVKEF DANFTYVQQS EFYLEPDSKY VFQVRCQETG KRNWQPWSSP FVHQTSQETG KRNWQPWSSP FVHQTSQTVS QVTAKSSHEP QKMEMLSATI FRGHPASGNH QDIG
• Sequence Length: 351

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Il23r recombinant protein

This protein is a subunit of the receptor for IL23A
IL23. This protein pairs with the receptor molecule IL12RB1
IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

NCBI and Uniprot Product Information

• NCBI GI #: 239052137
• NCBI GeneID: 209590
• NCBI Accession #: NP_653131.2
• NCBI GenBank Nucleotide #: NM_144548.1
• UniProt Accession #: Q8K4B4
• Molecular Weight: 73,453 Da
• NCBI Official Full Name: interleukin-23 receptor
• NCBI Official Synonym Full Names: interleukin 23 receptor
• NCBI Official Symbol: Il23r
• NCBI Official Synonym Symbols: IL-23R
• NCBI Protein Information: interleukin-23 receptor
• UniProt Protein Name: Interleukin-23 receptor
• Protein Family: Interleukin-23 receptor
• UniProt Gene Name: Il23r
• UniProt Synonym Gene Names: IL-23 receptor; IL-23R

Uniprot Description

Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis ().