Myotubularin (Mtm1) Recombinant Protein | Mtm1 recombinant protein
Recombinant Rat Myotubularin (Mtm1)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Myotubularin (Mtm1); Recombinant Rat Myotubularin (Mtm1); Mtm1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-602, full length protein
Sequence
MASSSASDCDAHPVERESMRKVSQDGVRQDMSKSGPRLPGESAITDKEVIYICPFSGPVKGRLYITNYRLYLRSLETDLAPILDVPLGVISRIEKMGGVTSRGENSYGLDITCKDLRNLRFALKQEGHSRRDIFDVLTRHAFPLAYNLPLFAFVNEEKFKVDGWAIYNPVEEYRRQGLPDRHWRISFVNQRYELCDTYPALLVVPYRASDDDLRRVATFRSRNRIPVLSWIHPENRAAIMRCSQPLVGVGGKRSRDDERYLDIIRETNKQTSKLTIYDARPGVNAVANKATGGGYEGEDAYPHAELSFLDIHNIHVMRESLRRVRDIVYPHVEEAHWLSSLESTHWLEHIKLLLTGAIRVADKVASGLSSVLVHCSDGWDRTAQLTTLAMLMLDGFYRSIEGFEILVQKEWISFGHKFSSRIGHGDKNHADADRSPIFLQFIDCVWQMTKQFPTAFEFNECFLVAILDHLYSCRFGTFLLNCEAARERQRLAERTVSVWSLINSNKDEFTNPFYARESNRVIYPVTSVRHLELWVNYYIRWNPRIRQQPHPMEQRYNELLALRDDYIKKLEELQLATPTKLTDSSTPPSGSAQIAPRMQTHF
Sequence Length
602
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Mtm1 recombinant protein
This gene encodes a dual-specificity phosphatase that acts on both phosphotyrosine and phosphoserine. It is required for muscle cell differentiation and mutations in this gene have been identified as being responsible for X-linked myotubular myopathy.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
69,480 Da
NCBI Official Full Name
myotubularin
NCBI Official Synonym Full Names
myotubularin 1
NCBI Official Symbol
Mtm1
NCBI Protein Information
myotubularin
UniProt Protein Name
Myotubularin
Protein Family
UniProt Gene Name
Mtm1
Uniprot Description
Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis ().
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Product Notes
The Mtm1 mtm1 (Catalog #AAA1369914) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-602, full length protein. The amino acid sequence is listed below: MASSSASDCD AHPVERESMR KVSQDGVRQD MSKSGPRLPG ESAITDKEVI YICPFSGPVK GRLYITNYRL YLRSLETDLA PILDVPLGVI SRIEKMGGVT SRGENSYGLD ITCKDLRNLR FALKQEGHSR RDIFDVLTRH AFPLAYNLPL FAFVNEEKFK VDGWAIYNPV EEYRRQGLPD RHWRISFVNQ RYELCDTYPA LLVVPYRASD DDLRRVATFR SRNRIPVLSW IHPENRAAIM RCSQPLVGVG GKRSRDDERY LDIIRETNKQ TSKLTIYDAR PGVNAVANKA TGGGYEGEDA YPHAELSFLD IHNIHVMRES LRRVRDIVYP HVEEAHWLSS LESTHWLEHI KLLLTGAIRV ADKVASGLSS VLVHCSDGWD RTAQLTTLAM LMLDGFYRSI EGFEILVQKE WISFGHKFSS RIGHGDKNHA DADRSPIFLQ FIDCVWQMTK QFPTAFEFNE CFLVAILDHL YSCRFGTFLL NCEAARERQR LAERTVSVWS LINSNKDEFT NPFYARESNR VIYPVTSVRH LELWVNYYIR WNPRIRQQPH PMEQRYNELL ALRDDYIKKL EELQLATPTK LTDSSTPPSG SAQIAPRMQT HF. It is sometimes possible for the material contained within the vial of "Myotubularin (Mtm1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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