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PAI-1 (Neutrophil Elastase inhibitor) Protein | SERPINE1 protein

Human PAI-1 (Neutrophil Elastase inhibitor)

Gene Names
SERPINE1; PAI; PAI1; PAI-1; PLANH1
Purity
>95% by SDS-PAGE analysis
Synonyms
PAI-1 (Neutrophil Elastase inhibitor); Human PAI-1 (Neutrophil Elastase inhibitor); SERPINE1 protein
Ordering
For Research Use Only!
Host
E. coli
Purity/Purification
>95% by SDS-PAGE analysis
Form/Format
Frozen liquid
Concentration
2.5 mg/ml (varies by lot)
Sequence Length
402
Buffer
0.05M Sodium Phosphate; 0.1M NaCl; 1mM EDTA; pH 6.6
Extinction Coefficient
1
Preparation and Storage
Store at -70 degree C. Shelf Life: 3 years from delivery
Related Product Information for SERPINE1 protein
This human PAI-1 variant contains a mutation at the active site to make it specific for inhibition of neutrophil elastase (R346V). Additional mutations provide resistance to cleavage (V343A) and increased stability (I91L). This preparation has low endotox

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
43,000
NCBI Official Full Name
plasminogen activator inhibitor 1
NCBI Official Synonym Full Names
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
NCBI Official Symbol
SERPINE1
NCBI Official Synonym Symbols
PAI; PAI1; PAI-1; PLANH1
NCBI Protein Information
plasminogen activator inhibitor 1; serpin E1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
UniProt Protein Name
Plasminogen activator inhibitor 1
UniProt Gene Name
SERPINE1
UniProt Synonym Gene Names
PAI1; PLANH1; PAI; PAI-1
UniProt Entry Name
PAI1_HUMAN

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Product Notes

The SERPINE1 serpine1 (Catalog #AAA135858) is a Protein produced from E. coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PAI-1 (Neutrophil Elastase inhibitor), Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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