Caspase-8 (Dredd) Recombinant Protein | Dredd recombinant protein
Recombinant Drosophila melanogaster Caspase-8 (Dredd)
Gene Names
Dredd; anon-1BCa; CASP8_DROME; CG7486; Dcp-2; DCP-2; dcp-2/dredd; Dcp-2/Dredd; DCP-2/DREDD; Dcp2; DCP2; dDredd; Dedd; DmelCG7486; dredd; DREDD; Dredd/DCP-2; EG:115C2.9; Redd
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Caspase-8 (Dredd); Recombinant Drosophila melanogaster Caspase-8 (Dredd); Dredd recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
243-400, Full length protein
Sequence
YCSTQIDALKLTRENAGIALIINQQKFHRNVSRDNMKFLSPDPLRRRDGTDVDKERLIEVFSSMGYNVEAYDNVDHMGIIERIRSACDRSLVRDSLVVFILSHGFEEAVYASNSIAMKITDIEDLLCSYDTLYYKPKLLIIQACQEKLVHKKKPNELF
Sequence Length
158
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
41,238 Da
NCBI Official Full Name
death related ced-3/Nedd2-like caspase, isoform E
NCBI Official Synonym Full Names
Death related ced-3/Nedd2-like caspase
NCBI Official Symbol
Dredd
NCBI Official Synonym Symbols
anon-1BCa; CASP8_DROME; CG7486; Dcp-2; DCP-2; dcp-2/dredd; Dcp-2/Dredd; DCP-2/DREDD; Dcp2; DCP2; dDredd; Dedd; DmelCG7486; dredd; DREDD; Dredd/DCP-2; EG:115C2.9; Redd
NCBI Protein Information
CG7486 gene product from transcript CG7486-RD
UniProt Protein Name
Caspase-8
UniProt Gene Name
Dredd
UniProt Synonym Gene Names
DCP2
Uniprot Description
Effector of the programmed cell death (PCD) activators rpr, grim and hid (PubMed:9740659). May play an apoptotic role in the germline as well as soma. Fadd interacts with Dredd to promote cleavage of Dredd and is necessary and sufficient for enhancing Dredd-induced apoptosis (PubMed:10934188). Plays a role in the innate immune response. Required for resistance to Gram-negative bacterial infection (PubMed:11269502). Diap2-mediated ubiquitination of Dredd is critical for processing of imd and rel and the subsequent expression of antimicrobial genes such as Dpt (PubMed:22549468).
Research Articles on Dredd
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Product Notes
The Dredd dredd (Catalog #AAA1347233) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 243-400, Full length protein. The amino acid sequence is listed below: YCSTQIDALK LTRENAGIAL IINQQKFHRN VSRDNMKFLS PDPLRRRDGT DVDKERLIEV FSSMGYNVEA YDNVDHMGII ERIRSACDRS LVRDSLVVFI LSHGFEEAVY ASNSIAMKIT DIEDLLCSYD TLYYKPKLLI IQACQEKLVH KKKPNELF. It is sometimes possible for the material contained within the vial of "Caspase-8 (Dredd), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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