UPF0532 protein C7orf60 (C7orf60) Recombinant Protein | C7orf60 recombinant protein
Recombinant Human UPF0532 protein C7orf60 (C7orf60)
Gene Names
BMT2; SAMTOR; C7orf60
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
UPF0532 protein C7orf60 (C7orf60); Recombinant Human UPF0532 protein C7orf60 (C7orf60); C7orf60 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-405, Full length protein
Sequence
MEPGAGGRNTARAQRAGSPNTPPPREQERKLEQEKLSGVVKSVHRRLRKKYREVGDFDKIWREHCEDEETLCEYAVAMKNLADNHWAKTCEGEGRIEWCCSVCREYFQNGGKRKALEKDEKRAVLATKTTPALNMHESSQLEGHLTNLSFTNPEFITELLQASGKIRLLDVGSCFNPFLKFEEFLTVGIDIVPAVESVYKCDFLNLQLQQPLQLAQDAIDAFLKQLKNPIDSLPGELFHVVVFSLLLSYFPSPYQRWICCKKAHELLVLNGLLLIITPDSSHQNRHAMMMKSWKIAIESLGFKRFKYSKFSHMHLMAFRKISLKTTSDLVSRNYPGMLYIPQDFNSIEDEEYSNPSCYVRSDIEDEQLAYGFTELPDAPYDSDSGESQASSIPFYELEDPILLLS
Sequence Length
405
Species
Human
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
46,324 Da
NCBI Official Full Name
S-adenosylmethionine sensor upstream of mTORC1
NCBI Official Synonym Full Names
base methyltransferase of 25S rRNA 2 homolog
NCBI Official Symbol
BMT2
NCBI Official Synonym Symbols
SAMTOR; C7orf60
NCBI Protein Information
S-adenosylmethionine sensor upstream of mTORC1
UniProt Protein Name
S-adenosylmethionine sensor upstream of mTORC1
UniProt Gene Name
BMT2
Uniprot Description
S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes (PubMed:29123071). Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling (PubMed:29123071). Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 signaling (PubMed:29123071). Probably also acts as a S-adenosyl-L-methionine-dependent methyltransferase (Potential).
Research Articles on C7orf60
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Product Notes
The C7orf60 bmt2 (Catalog #AAA1345506) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-405, Full length protein. The amino acid sequence is listed below: MEPGAGGRNT ARAQRAGSPN TPPPREQERK LEQEKLSGVV KSVHRRLRKK YREVGDFDKI WREHCEDEET LCEYAVAMKN LADNHWAKTC EGEGRIEWCC SVCREYFQNG GKRKALEKDE KRAVLATKTT PALNMHESSQ LEGHLTNLSF TNPEFITELL QASGKIRLLD VGSCFNPFLK FEEFLTVGID IVPAVESVYK CDFLNLQLQQ PLQLAQDAID AFLKQLKNPI DSLPGELFHV VVFSLLLSYF PSPYQRWICC KKAHELLVLN GLLLIITPDS SHQNRHAMMM KSWKIAIESL GFKRFKYSKF SHMHLMAFRK ISLKTTSDLV SRNYPGMLYI PQDFNSIEDE EYSNPSCYVR SDIEDEQLAY GFTELPDAPY DSDSGESQAS SIPFYELEDP ILLLS. It is sometimes possible for the material contained within the vial of "UPF0532 protein C7orf60 (C7orf60), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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