Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1) Recombinant Protein | LRWD1 recombinant protein
Recombinant Mouse Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1)
Gene Names
Lrwd1; Orca; AU042569; AW548074; 1200011O22Rik
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1); Recombinant Mouse Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1); LRWD1 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-648, Full length protein
Sequence
MAPLTPQLLLQRGRPKTDKLGKIQSLNLSGLQLLSEHLDPNLLGRLKKLRELDLSNNLLETLPANLGLSHLRILRCTNNQLGDVTALHQFPELEELNLEGNPFLTVSDNLKVSFLLPKLRKVNGKDTASTCSQVENLDRELMDRVTAHWQKFIATVSPEEETDKVRADFMRSAVRDVCYGPESLIEFTQWRVRMIAEELVASGGAQVQDAKVPVEHPQAAGASKFRAREVASKRPGKDPVTLPPSKRVRALPPAQAEGSPMGADGGQAALHLEPLHFLQCHSRNNSPKDLETQLWACAFEPAREEGHSRATSQTVATCGGEAVCVIDCQTGLVLHKYKVPGEEFFSVAWTALTVVTQAGHKKRWNMLAAAGLRGMVRLLHVRAGFCCSVIRAHKKAIATLCFSPSHETHLFTASYDKRIILWDIGVPNQDYKFQASQLLTLNCGSVPLRLCPVATCPDDFLLAGCEGGCYCWDVRLDQPQKQRVCEVNFIFSEDSKVSGQRVDGLAFVNEDVVASKGSGQGTIYLWSWSQTWAGRGRQSVLPVVILVRLQWSPTNLAYFSLSTCPGKNLVLCGDEEGSVWIYDVEHLLKEPPQATTLQPPTQILKWPQPTALGQPVTKTMINTVVANAAFTYLTALTDSNIVSIWRRC
Sequence Length
648
Species
Mouse
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
71,594 Da
NCBI Official Full Name
leucine-rich repeat and WD repeat-containing protein 1
NCBI Official Synonym Full Names
leucine-rich repeats and WD repeat domain containing 1
NCBI Official Symbol
Lrwd1
NCBI Official Synonym Symbols
Orca; AU042569; AW548074; 1200011O22Rik
NCBI Protein Information
leucine-rich repeat and WD repeat-containing protein 1
UniProt Protein Name
Leucine-rich repeat and WD repeat-containing protein 1
Protein Family
UniProt Gene Name
LRWD1
UniProt Synonym Gene Names
Orca; ORCA
Uniprot Description
Required for G1/S transition. Recruits and stabilizes the origin recognition complex (ORC) onto chromatin during G1 to establish pre-replication complex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histone methylation repressive marks on heterochromatin. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 and H4K20me3 in a cooperative manner with DNA methylation (). Required for silencing of major satellite repeats. May be important ORC2, ORC3 and ORC4 stability.
Research Articles on LRWD1
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Product Notes
The LRWD1 lrwd1 (Catalog #AAA1328390) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-648, Full length protein. The amino acid sequence is listed below: MAPLTPQLLL QRGRPKTDKL GKIQSLNLSG LQLLSEHLDP NLLGRLKKLR ELDLSNNLLE TLPANLGLSH LRILRCTNNQ LGDVTALHQF PELEELNLEG NPFLTVSDNL KVSFLLPKLR KVNGKDTAST CSQVENLDRE LMDRVTAHWQ KFIATVSPEE ETDKVRADFM RSAVRDVCYG PESLIEFTQW RVRMIAEELV ASGGAQVQDA KVPVEHPQAA GASKFRAREV ASKRPGKDPV TLPPSKRVRA LPPAQAEGSP MGADGGQAAL HLEPLHFLQC HSRNNSPKDL ETQLWACAFE PAREEGHSRA TSQTVATCGG EAVCVIDCQT GLVLHKYKVP GEEFFSVAWT ALTVVTQAGH KKRWNMLAAA GLRGMVRLLH VRAGFCCSVI RAHKKAIATL CFSPSHETHL FTASYDKRII LWDIGVPNQD YKFQASQLLT LNCGSVPLRL CPVATCPDDF LLAGCEGGCY CWDVRLDQPQ KQRVCEVNFI FSEDSKVSGQ RVDGLAFVNE DVVASKGSGQ GTIYLWSWSQ TWAGRGRQSV LPVVILVRLQ WSPTNLAYFS LSTCPGKNLV LCGDEEGSVW IYDVEHLLKE PPQATTLQPP TQILKWPQPT ALGQPVTKTM INTVVANAAF TYLTALTDSN IVSIWRRC. It is sometimes possible for the material contained within the vial of "Leucine-rich repeat and WD repeat-containing protein 1 (LRWD1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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