Probable spermidine synthase (speE) Recombinant Protein | speE recombinant protein
Recombinant Pyrococcus furiosus Probable spermidine synthase (speE)
NCBI and Uniprot Product Information
Uniprot Description
Involved in the biosynthesis of polyamines which are thought to support the growth of thermophilic microorganisms under high-temperature conditions. It seems that long-chain and branched-chain of polyamines effectively stabilize DNA and RNA, respectively. Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to various amine acceptors such as agmatine, cadaverine (1,5-diaminopentane), putrescine (1,4-diaminobutane) and 1,3-diaminopropane. The biosynthesis of norspermine and thermospermine from sym-norspermidine and spermidine has been also observed, but with a very low activity. The reaction involves a nucleophilic attack on the C-3 methylene of the propylamine moiety adjacent to the positively charged sulfur of decarboxy-AdoMet.
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Product Notes
The speE spee (Catalog #AAA1319786) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-281, Full length protein. The amino acid sequence is listed below: MERAFIEWYP RGYGVAFKIK KKIYEKLSKY QKIEVYETEG FGRLLALDGT VQLVTLGERS YHEPLVHPAM LAHPKPKRVL VIGGGDGGTV REVLQHDVDE VIMVEIDEDV IMVSKDLIKI DNGLLEAMLN GKHEKAKLTI GDGFEFIKNN RGFDVIIADS TDPVGPAKVL FSEEFYRYVY DALNNPGIYV TQAGSVYLFT DELISAYKEM KKVFDRVYYY SFPVIGYASP WAFLVGVKGD IDFTKIDRER AKKLQLEYYD PLMHETLFQM PKYIRETLQR L. It is sometimes possible for the material contained within the vial of "Probable spermidine synthase (speE), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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