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Tyrosine-protein kinase receptor TYRO3 (TYRO3) Recombinant Protein | TYRO3 recombinant protein

Recombinant Chicken Tyrosine-protein kinase receptor TYRO3 (TYRO3), partial

Gene Names
TYRO3; AXL; REK
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Tyrosine-protein kinase receptor TYRO3 (TYRO3); Recombinant Chicken Tyrosine-protein kinase receptor TYRO3 (TYRO3); partial; TYRO3 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
29-416
Sequence
AG MKFTGSPIKL KVSQGQPVKL NCSLEGMEDP EMLWIKDGAV VQSVDQVYIP VDEDHWIGFL SLKSVERTDS GKYWCQVENG GKKEESQQVW LIVEGVPYFT VEPEDVSVSP NAPFHMACAA VGPPEPVTIV WWMGDSRVGL PDISPSILNV SGINQSTMFS CEAHNVKGLS SSRTATVQIK AMPLPPLNVT VSQVTSSNAS VVWVPGFDGR APLHSCTLQV AESPDGQEVS TEVAPVPPFA YGVQGLKHST NYSVRVQCSN EMGSSPFTER VYFQTLELAP SSTPQNIHVI QRDPGLVLEW EGVAPDVLKE NVLGYRLEWI QDNVTQGEMI VQDTKANLTT WNPLKDLIIR VCVLNSAGCG PWSDLFLLEA QEVMGGQRQP PYGTSW
Sequence Length
388
Species
Chicken
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
96,402 Da
NCBI Official Full Name
tyrosine-protein kinase receptor TYRO3
NCBI Official Synonym Full Names
TYRO3 protein tyrosine kinase
NCBI Official Symbol
TYRO3
NCBI Official Synonym Symbols
AXL; REK
NCBI Protein Information
tyrosine-protein kinase receptor TYRO3
UniProt Protein Name
Tyrosine-protein kinase receptor TYRO3
UniProt Gene Name
TYRO3
UniProt Synonym Gene Names
REK; Rek

Uniprot Description

Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to several ligands. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces dimerization and autophosphorylation of TYRO3 on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, enhances PI3-kinase activity and activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes ().

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Product Notes

The TYRO3 tyro3 (Catalog #AAA1309702) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 29-416. The amino acid sequence is listed below: AG MKFTGSPIKL KVSQGQPVKL NCSLEGMEDP EMLWIKDGAV VQSVDQVYIP VDEDHWIGFL SLKSVERTDS GKYWCQVENG GKKEESQQVW LIVEGVPYFT VEPEDVSVSP NAPFHMACAA VGPPEPVTIV WWMGDSRVGL PDISPSILNV SGINQSTMFS CEAHNVKGLS SSRTATVQIK AMPLPPLNVT VSQVTSSNAS VVWVPGFDGR APLHSCTLQV AESPDGQEVS TEVAPVPPFA YGVQGLKHST NYSVRVQCSN EMGSSPFTER VYFQTLELAP SSTPQNIHVI QRDPGLVLEW EGVAPDVLKE NVLGYRLEWI QDNVTQGEMI VQDTKANLTT WNPLKDLIIR VCVLNSAGCG PWSDLFLLEA QEVMGGQRQP PYGTSW. It is sometimes possible for the material contained within the vial of "Tyrosine-protein kinase receptor TYRO3 (TYRO3), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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