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Suppressor of hairless protein homolog (rbpj) Recombinant Protein | rbpj recombinant protein

Recombinant Xenopus laevis Suppressor of hairless protein homolog (rbpj), partial

Gene Names
rbpj.S; csl; CBF1; rbpj; CBF-1; Su(H); lag-1; RBPSUH; XSu(H); xsu(h)1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Suppressor of hairless protein homolog (rbpj); Recombinant Xenopus laevis Suppressor of hairless protein homolog (rbpj); partial; rbpj recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-501aa, full length protein
Sequence
MQPGIPKYTPSAIQLAPVVTGKFGERPQPKRLTREAMRNYLKERGDQTVLILHAKVAQKSYGNEKRFFCPPPCVYLMGSGWKKKKEQMERDGCSEQESQPCAFIGIGNSEQEMQQLNLEGKNYCTAKTLYISDSDKRKHFMLSVKMFYGNSDDIGVFLSKRIKVISKPSKKKQSLKNADLCIASGTKVALFNRLRSQTVSTRYLHVEGGNFHASSQQWGAFYIHLLDDEESEGEEFTVRDGYIHYGQTVKLVCSVTGMALPRLIIRKVDKQTALLDADDPVSQLHKCAFYLKDTERMYLCLSQERIIQFQATPCPKEPNKEMINDGASWTIISTDKAEYTFYEGMGPINAPVTPVPVVESLQLNGGGDVAMLELTGQNFTPNLRVWFGDVEAETMYRCAESMLCVVPDISAFREGWRWVRQPVQVPVTLVRNDGVIYSTSLTFTYTPEPGPRPHCSAAGAILRANSSLLASNEPNTNSEGSYTNISTNSANVTSSTAAVVS
Sequence Length
481
Species
Xenopus laevis (African clawed frog)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,844 Da
NCBI Official Full Name
suppressor of hairless protein homolog
NCBI Official Synonym Full Names
recombination signal binding protein for immunoglobulin kappa J region S homeolog
NCBI Official Symbol
rbpj.S
NCBI Official Synonym Symbols
csl; CBF1; rbpj; CBF-1; Su(H); lag-1; RBPSUH; XSu(H); xsu(h)1
NCBI Protein Information
suppressor of hairless protein homolog
UniProt Protein Name
Suppressor of hairless protein homolog
UniProt Gene Name
rbpj
UniProt Synonym Gene Names
rbpsuh; suh

Uniprot Description

Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some NICD product of Notch proteins (Notch intracellular domain), it acts as a transcriptional activator that activates transcription of Notch target genes (). Required for the transcriptional activation of ESR1, suggesting that it is required during primary neurogenesis in embryos. Binds to the oxygen responsive element of COX4I2 and activates its transcription under hypoxia conditions (4% oxygen) ().

Research Articles on rbpj

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Product Notes

The rbpj rbpj (Catalog #AAA1303153) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-501aa, full length protein. The amino acid sequence is listed below: MQPGIPKYTP SAIQLAPVVT GKFGERPQPK RLTREAMRNY LKERGDQTVL ILHAKVAQKS YGNEKRFFCP PPCVYLMGSG WKKKKEQMER DGCSEQESQP CAFIGIGNSE QEMQQLNLEG KNYCTAKTLY ISDSDKRKHF MLSVKMFYGN SDDIGVFLSK RIKVISKPSK KKQSLKNADL CIASGTKVAL FNRLRSQTVS TRYLHVEGGN FHASSQQWGA FYIHLLDDEE SEGEEFTVRD GYIHYGQTVK LVCSVTGMAL PRLIIRKVDK QTALLDADDP VSQLHKCAFY LKDTERMYLC LSQERIIQFQ ATPCPKEPNK EMINDGASWT IISTDKAEYT FYEGMGPINA PVTPVPVVES LQLNGGGDVA MLELTGQNFT PNLRVWFGDV EAETMYRCAE SMLCVVPDIS AFREGWRWVR QPVQVPVTLV RNDGVIYSTS LTFTYTPEPG PRPHCSAAGA ILRANSSLLA SNEPNTNSEG SYTNISTNSA NVTSSTAAVV S. It is sometimes possible for the material contained within the vial of "Suppressor of hairless protein homolog (rbpj), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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