Mitochondrial cardiolipin hydrolase (zuc) Recombinant Protein | zuc recombinant protein
Recombinant Drosophila melanogaster Mitochondrial cardiolipin hydrolase (zuc), partial
NCBI and Uniprot Product Information
Uniprot Description
Cardiolipin hydrolase present at the mitochondrial outer membrane required for piRNA metabolic process. Acts by catalyzing the hydrolysis of cardiolipin (diphosphatidylglycerol) to form phosphatidate (phosphatidic acid or PA) at the mitochondrial outer membrane surface, promoting the piRNA metabolic process. Plays a key role in primary biogenesis of piRNAs and is required during oogenesis to repress transposable elements and prevent their mobilization. piRNAs mediate the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Involved in trans-silencing effect (TSE), a homology-dependent repression mechanism by which a P-transgene inserted in subtelomeric heterochromatin via its role in piRNA biogenesis.
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Product Notes
The zuc zuc (Catalog #AAA1297150) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 31-253. The amino acid sequence is listed below: EVIWKLVQCS RSKREKASRV HEVIIFNELG EICAAVHMRN SSMGSQKPQV SPCCNTHCSL RNVAKIVEQI DRAVYSIDLA IYTFTSLFLA DSIKRALQRG VIIRIISDGE MVYSKGSQIS MLAQLGVPVR VPITTNLMHN KFCIIDGFER VEEIRLLRKL KFMRPCYSIV ISGSVNWTAL GLGGNWENCI ITADDKLTAT FQAEFQRMWR AFAKTEGSQI QLK. It is sometimes possible for the material contained within the vial of "Mitochondrial cardiolipin hydrolase (zuc), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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