CORO2A cdna clone
CORO2A cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Uniprot Description
coronin 2A: a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 5 WD repeats, and has a structural similarity with actin-binding proteins: the D. discoideum coronin and the human p57 protein, suggesting that this protein may also be an actin-binding protein that regulates cell motility. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 9q22.3
Cellular Component: actin cytoskeleton; transcriptional repressor complex
Molecular Function: actin filament binding
Biological Process: actin cytoskeleton organization and biogenesis
Research Articles on CORO2A
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Product Notes
The CORO2A coro2a (Catalog #AAA1278923) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtcatggc acccccagta ccggagctcc aagttccgtc atgtctttgg caaaccagcc agcaaggaga actgctacga ctccgtgcct atcacccgca gcgttcacga caaccacttc tgtgccgtga acccccactt cattgcagtt gtgactgagt gtgctggtgg aggggccttc ctcgtcatcc ccctgcacca gacagggaag ttggaccccc actacccaaa agtctgcggg cacagaggca acgttttgga tgtcaagtgg aacccttttg atgattttga gatcgcctcc tgttctgaag atgccacaat taagatctgg agcatcccca agcagctgct gaccaggaac ctcacggcct acaggaagga actcgtgggc cacgcgcgca gagtaggcct ggtggagtgg caccccacgg ccgccaacat cctcttcagt gctggctatg actacaaggt gatgatctgg aacctggata caaaggagtc tgtcatcaca agccccatga gtacgattag ctgtcaccaa gatgtgatcc tctccatgtc cttcaacacc aacggcagcc tgttggccac cacctgcaaa gaccgcaaga ttcgggttat tgacccccga gcagggaccg tcctccagga ggccagctac aaagggcacc gggccagcaa agtgctgttt ctggggaacc tgaagaagct gatgtccaca ggcacatccc gatggaacaa ccggcaggtg gccttgtggg accaggataa cctctctgtg cctctgatgg aggaggacct ggacggctcc tcgggcgtgc tgtttccctt ctatgacgcg gacaccagca tgctctacgt ggtggggaag ggagatggca acatccgcta ctacgaggtg agcgccgaca agcctcacct gagctacctg actgagtacc gctcctataa cccacagaag gggatcggtg tcatgccaaa gagaggactc gacgtgtcct cctgcgagat cttccgcttc tacaagctga tcacaaccaa aagcctcatc gagcccatct ccatgattgt gccccggcgg tcagaatcct accaagagga catataccct ccaacagcag gggcccagcc ctccctgacg gcccaggagt ggctcagcgg gatgaatcga gacccaatcc tggtgtccct taggcctggc tctgagctgc tgagacccca cccactgcct gcagagagac ctatcttcaa ttccatggcc ccagcctcac cccggctctt gaatcagaca gaaaagctgg ctgcagaaga tggctggagg tcttcctccc tgttggagga gaagatgcca aggtgggcag cagaacacag gctggaggag aagaaaacct ggctgacaaa tggctttgac gttttcgaat gccccccacc aaagacagag aatgagttgc tgcagatgtt ctaccggcaa caggaggaga tccgaaggct ccgggagctg ttgacccagc gagaggtcca ggccaaacag ttggaactgg agatcaaaaa cttgcggatg ggctcagagc agctctga. It is sometimes possible for the material contained within the vial of "CORO2A, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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