ZFYVE9 cdna clone
ZFYVE9 cDNA Clone
Gene Names
ZFYVE9; NSP; SARA; MADHIP; SMADIP; PPP1R173
Synonyms
ZFYVE9; ZFYVE9 cDNA Clone; ZFYVE9 cdna clone
Sequence
atggagaattacttccaagcagaagcttacaacctggacaaggtgttagatgaatttgaacaaaacgaagatgaaacagtttcttctactttattggatacaaagtggaataagattctagatcccccttctcaccggctgtcatttaaccctactttggccagtgtgaatgaatctgcagtttctaatgagtcacaaccacaactgaaagtcttctccctggctcattcagctcccctgaccacagaggaagaggatcactgtgctaatggacaggactgtaatctaaatccagagattgccacaatgtggattgatgaaaatgctgttgcagaagaccagttaattaagagaaactatagttgggatgatcaatgcagtgctgttgaagtgggagagaagaaatgtggaaacctggcttgtctgccagatgagaagaatgttcttgttgtagccgtcatgcataactgtgataaaaggacattacaaaacgatttacaggattgtaataattataatagtcaatcccttatggatgcttttagctgttcactggataatgaaaacagacaaactgatcaatttagttttagtataaatgagtccactgaaaaagatatgaattcagagaaacaaatggatccattgaatagaccgaaaacagaggggagatctgttaaccatctgtgtcctacttcatctgatagtctagccagtgtctgttccccttcacaattaaaggatgacggaagtataggtagagacccctccatgtctgcgattacaagtttaacggttgattcagtaatctcatcccagggaacagatggatgtcctgctgttaaaaagcaagagaactatataccagatgaggacctcactggcaaaatcagctctcctaggacagatctagggagtccaaattccttttcccacatgagtgaggggattttgatgaaaaaagagccagcagaggagagcaccactgaagaatccctccggtctggtttacctttgcttctcaaaccagacatgcctaatgggtctggaaggaataatgactgtgaacggtgttcagattgccttgtgcctaatgaagttagggctgatgaaaatgaaggttatgaacatgaagaaactcttggcactacagaattccttaatatgacagagcatttctctgaatctcaggacatgactaattggaagttgactaaactaaatgagatgaatgatagccaagtaaacgaagaaaaggaaaagtttctacagattagtcagcctgaggacactaatggtgatagtggaggacagtgtgttggattggcagatgcaggtctagatttaaaaggaacttgcattagtgaaagtgaagaatgtgatttctccactgttatagacacaccagcagcaaattatctatctaatggttgtgattcctatggaatgcaagacccaggtgtttcttttgttccaaagactttaccctccaaagaagattcagtaacagaagaaaaagaaatagaggaaagcaagtcagaatgctactcaaatatttatgaacagagaggaaatgaggccacagaagggagtggactacttttaaacagcactggtgacctaatgaagaaaaattatttacataatttctgtagtcaagttccatcagtgcttgggcaatcttcccccaaggtagtagcaagcctgccatctatcagtgttccttttggtggtgcaagacccaagcaaccttctaatcttaaacttcaaattccaaagccattatcagaccatttacaaaatgactttcctgcaaacagtggaaataatactaaaaataaaaatgatattcttgggaaagcaaaattaggggaaaactcagcaaccaatgtatgcagtccatctttgggaaacatctctaatgtcgatacaaatggggaacatttagaaagttatgaggctgagatctccactagaccatgccttgcattagctccagatagcccagataatgatctcagagctggtcagtttggaatttctgccagaaagccattcaccactctgggtgaggtggctccagtatgggtaccggattctcaggctccaaattgcatgaaatgtgaagccaggtttacattcaccaaaaggaggcatcactgcagagcatgtgggaaggttttctgtgcttcctgctgtagcctgaaatgtaaactgttatacatggacagaaaggaagctagagtgtgtgtaatctgccattcagtgctaatgaatgctcaagcctgggagaacatgatgagtgcctcaagccagagccctaaccctaacaatcctgctgaatactgttctactatccctcccttgcagcaagctcaggcctcaggagctctgagctctccacctcccactgtgatggtacctgtgggagttttaaagcaccctggagcagaagtggctcagcccagagagcagaggcgagtttggtttgctgatgggatcttgcccaatggagaagttgctgatgcagccaaattaacaatgaatggaacttcctctgcaggaaccctggctgtgtcacacgacccagtcaagccagtaactaccagtcctctaccagcagagacggatatttgtctattctctgggagtataactcaggttggaagtcctgttggaagtgcaatgaatcttattcctgaagatggccttcctcccattctcatctccactggtgtaaaaggagactatgctgtggaagagaaaccatcacagatttcagtaatgcagcagttggaggatggtggccctgacccacttgtatttgttttaaatgcaaatttgttgtcaatggttaaaattgtaaattatgtgaacaggaagtgctggtgtttcacaaccaagggaatgcatgcagtgggtcagtctgagatagtcattcttctacagtgtttaccggatgaaaagtgtttgccaaaggatatctttaatcactttgtgcagctttatcgggatgctctggcagggaatgtggtgagcaacttgggacattccttcttcagtcaaagtttccttggcagtaaagaacatggtggattcttatatgtgacatctacctaccagtcactgcaagacctagtactcccaaccccaccttacttgtttgggattcttatccagaaatgggaaactccttgggctaaagtatttcctatccgtctgatgttgagacttggagctgaatatcgactttatccatgcccactattcagtgtcagatttcggaagccattgtttggagagacggggcataccatcatgaatcttcttgcagacttcagaaattaccagtataccttgccagtagttcaaggtttggtggttgatatggaagttcggaaaactagcatcaaaattcccagcaacagatacaatgagatgatgaaagccatgaacaagtccaatgagcatgtcctggcaggaggtgcctgcttcaatgaaaaggcagactctcatcttgtgtgtgtacagaatgatgatggaaactatcagacccaggctatcagtattcacaatcagcccagaaaagtgactggtgccagtttctttgtgttcagtggcgctctgaaatcctcttctggataccttgccaagtccagtattgtggaagatggtgttatggtccagattactgcagagaacatggattccttgaggcaggcactgcgagagatgaaggacttcaccatcacctgtgggaaggcggacgcggaggaaccccaggagcacatccacatccagtgggtggatgatgacaagaacgttagcaagggtgtcgtaagtcctatagatgggaagtccatggagactataacaaatgtgaagatattccatggatcagaatataaagcaaatggaaaagtaatcagatggacagaggtgtttttcctagaaaacgatgaccagcacaattgcctcagtgatcctgcagatcacagtagattgactgagcatgttgccaaagctttttgccttgctctctgtcctcacctgaaacttctgaaggaagatggaatgaccaaactgggactacgtgtgacacttgactcagatcaggttggctatcaagcagggagcaatggccagccccttccctcgcagtacatgaatgatctggacagcgccttggtgccggtgatccatggaggggcctgccagcttagtgagggccccgttgtcatggaactcatcttttatattctggaaaacatcgtataa
Sequence Length
4278
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
83,721 Da
NCBI Official Full Name
Homo sapiens zinc finger, FYVE domain containing 9, mRNA
NCBI Official Synonym Full Names
zinc finger FYVE-type containing 9
NCBI Official Symbol
ZFYVE9
NCBI Official Synonym Symbols
NSP; SARA; MADHIP; SMADIP; PPP1R173
NCBI Protein Information
zinc finger FYVE domain-containing protein 9
UniProt Protein Name
Zinc finger FYVE domain-containing protein 9
Protein Family
UniProt Gene Name
ZFYVE9
UniProt Synonym Gene Names
MADHIP; SARA; SMADIP; Madh-interacting protein; NSP; hSARA
UniProt Entry Name
ZFYV9_HUMAN
NCBI Description
This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]
Uniprot Description
SARA: Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Adaptor/scaffold
Chromosomal Location of Human Ortholog: 1p32.3
Cellular Component: early endosome membrane
Molecular Function: phosphatidylinositol binding; protein binding
Biological Process: SMAD protein complex assembly; SMAD protein nuclear translocation; transforming growth factor beta receptor signaling pathway
Research Articles on ZFYVE9
Similar Products
Product Notes
The ZFYVE9 zfyve9 (Catalog #AAA1278614) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggagaatt acttccaagc agaagcttac aacctggaca aggtgttaga tgaatttgaa caaaacgaag atgaaacagt ttcttctact ttattggata caaagtggaa taagattcta gatccccctt ctcaccggct gtcatttaac cctactttgg ccagtgtgaa tgaatctgca gtttctaatg agtcacaacc acaactgaaa gtcttctccc tggctcattc agctcccctg accacagagg aagaggatca ctgtgctaat ggacaggact gtaatctaaa tccagagatt gccacaatgt ggattgatga aaatgctgtt gcagaagacc agttaattaa gagaaactat agttgggatg atcaatgcag tgctgttgaa gtgggagaga agaaatgtgg aaacctggct tgtctgccag atgagaagaa tgttcttgtt gtagccgtca tgcataactg tgataaaagg acattacaaa acgatttaca ggattgtaat aattataata gtcaatccct tatggatgct tttagctgtt cactggataa tgaaaacaga caaactgatc aatttagttt tagtataaat gagtccactg aaaaagatat gaattcagag aaacaaatgg atccattgaa tagaccgaaa acagagggga gatctgttaa ccatctgtgt cctacttcat ctgatagtct agccagtgtc tgttcccctt cacaattaaa ggatgacgga agtataggta gagacccctc catgtctgcg attacaagtt taacggttga ttcagtaatc tcatcccagg gaacagatgg atgtcctgct gttaaaaagc aagagaacta tataccagat gaggacctca ctggcaaaat cagctctcct aggacagatc tagggagtcc aaattccttt tcccacatga gtgaggggat tttgatgaaa aaagagccag cagaggagag caccactgaa gaatccctcc ggtctggttt acctttgctt ctcaaaccag acatgcctaa tgggtctgga aggaataatg actgtgaacg gtgttcagat tgccttgtgc ctaatgaagt tagggctgat gaaaatgaag gttatgaaca tgaagaaact cttggcacta cagaattcct taatatgaca gagcatttct ctgaatctca ggacatgact aattggaagt tgactaaact aaatgagatg aatgatagcc aagtaaacga agaaaaggaa aagtttctac agattagtca gcctgaggac actaatggtg atagtggagg acagtgtgtt ggattggcag atgcaggtct agatttaaaa ggaacttgca ttagtgaaag tgaagaatgt gatttctcca ctgttataga cacaccagca gcaaattatc tatctaatgg ttgtgattcc tatggaatgc aagacccagg tgtttctttt gttccaaaga ctttaccctc caaagaagat tcagtaacag aagaaaaaga aatagaggaa agcaagtcag aatgctactc aaatatttat gaacagagag gaaatgaggc cacagaaggg agtggactac ttttaaacag cactggtgac ctaatgaaga aaaattattt acataatttc tgtagtcaag ttccatcagt gcttgggcaa tcttccccca aggtagtagc aagcctgcca tctatcagtg ttccttttgg tggtgcaaga cccaagcaac cttctaatct taaacttcaa attccaaagc cattatcaga ccatttacaa aatgactttc ctgcaaacag tggaaataat actaaaaata aaaatgatat tcttgggaaa gcaaaattag gggaaaactc agcaaccaat gtatgcagtc catctttggg aaacatctct aatgtcgata caaatgggga acatttagaa agttatgagg ctgagatctc cactagacca tgccttgcat tagctccaga tagcccagat aatgatctca gagctggtca gtttggaatt tctgccagaa agccattcac cactctgggt gaggtggctc cagtatgggt accggattct caggctccaa attgcatgaa atgtgaagcc aggtttacat tcaccaaaag gaggcatcac tgcagagcat gtgggaaggt tttctgtgct tcctgctgta gcctgaaatg taaactgtta tacatggaca gaaaggaagc tagagtgtgt gtaatctgcc attcagtgct aatgaatgct caagcctggg agaacatgat gagtgcctca agccagagcc ctaaccctaa caatcctgct gaatactgtt ctactatccc tcccttgcag caagctcagg cctcaggagc tctgagctct ccacctccca ctgtgatggt acctgtggga gttttaaagc accctggagc agaagtggct cagcccagag agcagaggcg agtttggttt gctgatggga tcttgcccaa tggagaagtt gctgatgcag ccaaattaac aatgaatgga acttcctctg caggaaccct ggctgtgtca cacgacccag tcaagccagt aactaccagt cctctaccag cagagacgga tatttgtcta ttctctggga gtataactca ggttggaagt cctgttggaa gtgcaatgaa tcttattcct gaagatggcc ttcctcccat tctcatctcc actggtgtaa aaggagacta tgctgtggaa gagaaaccat cacagatttc agtaatgcag cagttggagg atggtggccc tgacccactt gtatttgttt taaatgcaaa tttgttgtca atggttaaaa ttgtaaatta tgtgaacagg aagtgctggt gtttcacaac caagggaatg catgcagtgg gtcagtctga gatagtcatt cttctacagt gtttaccgga tgaaaagtgt ttgccaaagg atatctttaa tcactttgtg cagctttatc gggatgctct ggcagggaat gtggtgagca acttgggaca ttccttcttc agtcaaagtt tccttggcag taaagaacat ggtggattct tatatgtgac atctacctac cagtcactgc aagacctagt actcccaacc ccaccttact tgtttgggat tcttatccag aaatgggaaa ctccttgggc taaagtattt cctatccgtc tgatgttgag acttggagct gaatatcgac tttatccatg cccactattc agtgtcagat ttcggaagcc attgtttgga gagacggggc ataccatcat gaatcttctt gcagacttca gaaattacca gtataccttg ccagtagttc aaggtttggt ggttgatatg gaagttcgga aaactagcat caaaattccc agcaacagat acaatgagat gatgaaagcc atgaacaagt ccaatgagca tgtcctggca ggaggtgcct gcttcaatga aaaggcagac tctcatcttg tgtgtgtaca gaatgatgat ggaaactatc agacccaggc tatcagtatt cacaatcagc ccagaaaagt gactggtgcc agtttctttg tgttcagtgg cgctctgaaa tcctcttctg gataccttgc caagtccagt attgtggaag atggtgttat ggtccagatt actgcagaga acatggattc cttgaggcag gcactgcgag agatgaagga cttcaccatc acctgtggga aggcggacgc ggaggaaccc caggagcaca tccacatcca gtgggtggat gatgacaaga acgttagcaa gggtgtcgta agtcctatag atgggaagtc catggagact ataacaaatg tgaagatatt ccatggatca gaatataaag caaatggaaa agtaatcaga tggacagagg tgtttttcct agaaaacgat gaccagcaca attgcctcag tgatcctgca gatcacagta gattgactga gcatgttgcc aaagcttttt gccttgctct ctgtcctcac ctgaaacttc tgaaggaaga tggaatgacc aaactgggac tacgtgtgac acttgactca gatcaggttg gctatcaagc agggagcaat ggccagcccc ttccctcgca gtacatgaat gatctggaca gcgccttggt gccggtgatc catggagggg cctgccagct tagtgagggc cccgttgtca tggaactcat cttttatatt ctggaaaaca tcgtataa. It is sometimes possible for the material contained within the vial of "ZFYVE9, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
