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Western Blot (WB) (Western blot analysis of SARA expression in Hela (A) whole cell lysates.)

Rabbit SARA Polyclonal Antibody | anti-SARA antibody

Anti-SARA Antibody

Gene Names
ZFYVE9; NSP; SARA; MADHIP; SMADIP; PPP1R173
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunoprecipitation
Purity
Purified by immunogen affinity chromatography
Synonyms
SARA; Polyclonal Antibody; Anti-SARA Antibody; MADHIP; SMADIP; Zinc finger FYVE domain-containing protein 9; Mothers against decapentaplegic homolog-interacting protein; Madh-interacting protein; Novel serine protease; NSP; Receptor activation anchor; hSARA; Smad anchor for receptor activation; anti-SARA antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of SARA protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
762
Applicable Applications for anti-SARA antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes
WB: 1/500 - 1/2000
IP: 1/50 - 1/100
Immunogen
Recombinant full length protein of human SARA
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of SARA expression in Hela (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of SARA expression in Hela (A) whole cell lysates.)
Related Product Information for anti-SARA antibody
Rabbit polyclonal antibody to SARA

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
83,721 Da
NCBI Official Full Name
zinc finger FYVE domain-containing protein 9 isoform 3
NCBI Official Synonym Full Names
zinc finger FYVE-type containing 9
NCBI Official Symbol
ZFYVE9
NCBI Official Synonym Symbols
NSP; SARA; MADHIP; SMADIP; PPP1R173
NCBI Protein Information
zinc finger FYVE domain-containing protein 9
UniProt Protein Name
Zinc finger FYVE domain-containing protein 9
Protein Family
UniProt Gene Name
ZFYVE9
UniProt Synonym Gene Names
MADHIP; SARA; SMADIP; Madh-interacting protein; NSP; hSARA

NCBI Description

This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013]

Uniprot Description

Early endosomal protein that functions to recruit SMAD2/SMAD3 to intracellular membranes and to the TGF-beta receptor. Plays a significant role in TGF-mediated signaling by regulating the subcellular location of SMAD2 and SMAD3 and modulating the transcriptional activity of the SMAD3/SMAD4 complex. Possibly associated with TGF-beta receptor internalization.

Research Articles on SARA

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Product Notes

The SARA zfyve9 (Catalog #AAA8292687) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SARA Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SARA can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP). WB: 1/500 - 1/2000 IP: 1/50 - 1/100. Researchers should empirically determine the suitability of the SARA zfyve9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SARA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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