RAD54L cdna clone
RAD54L cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, Dec 2008]
Uniprot Description
RAD54L: Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments. May play also an essential role in telomere length maintenance and telomere capping in mammalian cells. Belongs to the SNF2/RAD54 helicase family.
Protein type: Cell cycle regulation; Helicase; EC 3.6.1.-; EC 3.6.4.-; DNA repair, damage
Chromosomal Location of Human Ortholog: 1p32
Cellular Component: nucleoplasm; nucleus
Molecular Function: protein binding
Biological Process: DNA recombination; DNA repair; meiosis
Disease: Breast Cancer; Lymphoma, Non-hodgkin, Familial
Research Articles on RAD54L
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Product Notes
The RAD54L rad54l (Catalog #AAA1278226) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGGAGGA GCTTGGCTCC CAGCCAGCTG GCCAAGAGAA AACCTGAAGG CAGGTCCTGT GATGATGAAG ACTGGCAACC TGGCCTAGTG ACTCCTAGGA AACGGAAATC CAGCAGTGAG ACCCAGATCC AGGAGTGTTT CCTGTCTCCT TTTCGGAAAC CTTTGAGTCA GCTAACCAAT CAACCACCTT GTCTGGACAG CAGTCAGCAT GAAGCATTTA TTCGAAGCAT TTTGTCAAAG CCTTTCAAAG TCCCCATTCC AAATTATCAA GGTCCTCTGG GCTCTCGAGC ATTGGGCCTG AAAAGGGCTG GGGTCCGCCG GGCCCTCCAT GACCCCCTGG AAAAAGATGC CTTGGTTCTG TATGAGCCTC CCCCGCTGAG CGCTCATGAC CAGCTGAAGC TTGACAAGGA GAAACTCCCT GTCCATGTGG TTGTTGACCC TATTCTCAGT AAGGTTTTGC GGCCTCATCA GAGAGAGGGA GTGAAATTCC TGTGGGAGTG TGTCACCAGT CGGCGCATCC CTGGCAGCCA TGGCTGCATC ATGGCTGATG AGATGGGCCT AGGAAAGACG CTGCAGTGCA TCACATTGAT GTGGACACTT TTACGCCAGA GTCCAGAGTG CAAGCCAGAA ATTGACAAGG CAGTGGTGGT GTCGCCTTCC AGCCTGGTGA AGAACTGGTA CAATGAGGTT GGGAAATGGC TCGGAGGGAG GATCCAACCT CTGGCCATCG ATGGAGGATC TAAGGATGAA ATAGACCAAA AGCTGGAAGG ATTCATGAAC CAGCGTGGAG CCAGGGTGTC TTCTCCCATC CTCATCATTT CCTATGAGAC CTTCCGCCTT CATGTTGGAG TCCTCCAGAA AGGAAGTGTT GGTCTGGTCA TATGTGACGA GGGACACAGG CTCAAGAACT CTGAGAATCA GACTTACCAA GCCCTGGACA GCTTGAACAC CAGCCGGCGG GTGCTCATCT CCGGAACTCC CATCCAGAAT GATCTGCTTG AGTATTTCAG CTTGGTACAT TTTGTTAATT CCGGCATCCT AGGGACTGCC CATGAATTCA AGAAGCATTT TGAATTGCCA ATTTTGAAGG GTCGAGACGC TGCTGCTAGT GAGGCAGACA GGCAGCTAGG AGAGGAGCGG CTGCGGGAGC TCACCAGCAT TGTGAATAGA TGCCTGATAC GGAGGACTTC TGATATCCTT TCTAAATATC TGCCTGTGAA GATTGAGCAG GTCGTTTGTT GTAGGCTGAC ACCCCTTCAG ACTGAGTTAT ACAAGAGGTT TCTGAGACAA GCCAAACCGG CAGAAGAATT GCTTGAGGGC AAGATGAGTG TGTCTTCCCT TTCTTCCATC ACCTCGCTAA AGAAGCTTTG TAATCATCCA GCTCTAATCT ATGATAAGTG TGTGGAAGAG GAGGATGGCT TTGTGGGTGC CTTGGACCTC TTCCCTCCTG GTTACAGCTC TAAGGCCCTG GAGCCCCAGC TGTCAGGTAA GATGCTGGTC CTGGATTATA TTCTGGCGGT GACCCGAAGC CGTAGCAGTG ACAAAGTAGT GCTGGTGTCG AATTACACCC AGACTTTGGA TCTCTTTGAG AAGCTGTGCC GTGCCCGAAG GTACTTATAC GTCCGCCTGG ATGGCACGAT GTCCATTAAG AAGCGAGCCA AGGTTGTAGA ACGCTTCAAT AGTCCATCGA GCCCTGACTT TGTCTTCATG CTGAGCAGCA AAGCTGGGGG CTGTGGCCTC AATCTCATTG GGGCTAACCG GCTGGTCATG TTTGACCCTG ACTGGAACCC AGCCAATGAT GAACAAGCCA TGGCCCGGGT CTGGCGAGAT GGTCAAAAGA AGACTTGCTA TATCTACCGC CTGCTGTCTG CAGGGACCAT TGAGGAGAAG ATCTTCCAGC GTCAGAGCCA CAAGAAGGCA CTGAGCAGCT GTGTGGTGGA TGAGGAGCAG GATGTAGAGC GCCACTTCTC TCTGGGCGAG TTGAAGGAGC TGTTTATCCT GGATGAAGCT AGCCTCAGTG ACACACATGA CAGGTTGCAC TGCCGACGTT GTGTCAACAG CCGTCAGATC CGGCCACCCC CTGATGGTTC TGACTGCACT TCAGACCTGG CAGGGTGGAA CCACTGCACT GATAAGTGGG GGCTCCGGGA TGAGGTACTC CAGGCTGCCT GGGATGCTGC CTCCACTGCT ATCACCTTCG TCTTCCACCA GCGTTCTCAT GAGGAGCAGC GGGGCCTCCG CTGA. It is sometimes possible for the material contained within the vial of "RAD54L, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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