MAP3K13 cdna clone
MAP3K13 cDNA Clone
Gene Names
MAP3K13; LZK; MLK; MEKK13
Synonyms
MAP3K13; MAP3K13 cDNA Clone; MAP3K13 cdna clone
Sequence
ATGTCATTTGCTGGCACGGTCGCATGGATGGCGCCAGAGGTGATACGGAATGAACCTGTCTCTGAAAAAGTTGATATATGGTCTTTTGGAGTGGTGCTTTGGGAGCTGCTGACAGGAGAGATCCCTTACAAAGATGTAGATTCTTCAGCCATTATCTGGGGTGTTGGAAGCAACAGCCTCCACCTTCCAGTTCCTTCCACTTGCCCTGATGGATTCAAAATCCTTATGAAACAGACGTGGCAGAGTAAACCTCGAAACCGACCTTCTTTTCGGCAGACACTCATGCATTTAGACATTGCCTCTGCAGATGTACTTGCCACCCCACAAGAAACTTACTTCAAGTCTCAGGCTGAATGGAGAGAAGAAGTGAAAAAACATTTTGAGAAGATCAAAAGTGAAGGAACTTGTATACACCGGTTAGATGAAGAACTGATTCGAAGGCGCAGAGAAGAGCTCAGGCATGCGCTGGATATTCGTGAACACTATGAGCGGAAGCTTGAGCGGGCGAATAATTTATACATGGAATTGAGTGCCATCATGCTGCAGCTAGAAATGCGGGAGAAGGAGCTCATTAAGCGTGAGCAAGCAGTGGAAAAGAAGTATCCTGGGACCTACAAACGACACCCTGTTCGTCCTATCATCCATCCCAATGCCATGGAGAAACTCATGAAAAGGAAAGGAGTGCCTCACAAATCTGGGATGCAGACCAAACGGCCAGACTTGTTGAGATCAGAAGGGATCCCCACCACAGAAGTGGCTCCCACTGCATCCCCTTTGTCCGGAAGTCCCAAAATGTCCACTTCTAGCAGCAAGAGCCGATATCGAAGCAAACCACGCCACCGCCGAGGGAATAGCAGAGGCAGCCATAGTGACTTTGCCGCAATCTTGAAAAACCAGCCAGCCCAGGAAAATTCACCCCATCCCACTTACCTGCACCAAGCTCAATCCCAATACCCTTCTCTTCATCACCATAATTCTCTGCAGCAGCAATACCAGCAGCCCCCTCCTGCCATGTCCCAGAGTCACCATCCCAGACTCAATATGCACGGACAGGACATAGCAACCTGCGCCAACAACCTGAGGTATTTCGGCCCAGCAGCAGCCCTGCGGAGCCCACTCAGCAACCATGCTCAGAGACAGCTGCCCGGCTCGAGCCCTGACCTCATCTCCACAGCCATGGCTGCAGACTGCTGGAGAAGTTCTGAGCCTGACAAGGGCCAAGCTGGTCCCTGGGGCTGTTGCCAGGCTGACGCTTATGACCCCTGCCTTCAGTGCAGGCCAGAACAGTATGGGTCCTTAGACATACCCTCTGCTGAGCCAGTGGGGAGGAGCCCTGACCTTTCCAAGTCACCAGCACATAATCCTCTCTTGGAAAACGCCCAGAGTTCTGAGAAAACGGAAGAAAATGAATTCAGCGGCTGTAGGTCTGAGTCATCCCTCGGCACCTCTCATCTCGGCACCCCTCCAGCGCTACCTCGAAAAACAAGGCCTCTGCAGAAGAGTGGAGATGACTCCTCAGAAGAGGAAGAAGGGGAAGTAGATAGTGAAGTTGAATTTCCACGAAGACAGAGGCCCCATCGCTGTATCAGCAGCTGCCAGTCATATTCAACCTTTAGCTCTGAGAATTTCTCTGTGTCTGATGGAGAAGAGGGAAATACCAGTGACCACTCAAACAGTCCTGATGAGTTAGCTGATAAACTTGAAGACCGCTTGGCAGAGAAGCTAGACGACCTGCTGTCCCAGACGCCAGAGATTCCCATTGACATATCCTCACACTCGGATGGGCTCTCTGACAAGGAGTGTGCCGTGCGCCGTGTGAAGACTCAGATGTCTCTGGGCAAGCTGTGTGTGGAGGAACGTGGCTATGAGAACCCCATGCAGTTTGAAGAATCGGACTGTGACTCTTCAGATGGGGAGTGTTCTGATGCCACAGTTAGGACCAATAAACACTACAGCTCTGCTACCTGGTAA
Sequence Length
1971
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
14,073 Da
NCBI Official Full Name
Homo sapiens mitogen-activated protein kinase kinase kinase 13, mRNA
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase kinase 13
NCBI Official Symbol
MAP3K13
NCBI Official Synonym Symbols
LZK; MLK; MEKK13
NCBI Protein Information
mitogen-activated protein kinase kinase kinase 13
UniProt Protein Name
Mitogen-activated protein kinase kinase kinase 13
Protein Family
UniProt Gene Name
MAP3K13
UniProt Synonym Gene Names
MLK
UniProt Entry Name
M3K13_HUMAN
NCBI Description
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif. This kinase can phosphorylate and activate MAPK8/JNK, MAP2K7/MKK7, which suggests a role in the JNK signaling pathway. [provided by RefSeq, Jul 2008]
Uniprot Description
LZK: a TKL kinase of the MLK family. Synergizes with antioxidant protein-1 to activate NF-kappaB. Forms a functional signaling complex with JIP-1, a scaffold protein of the c-Jun NH(2)-terminal kinase pathway. This kinase can phosphorylate and activate JNK and MKK7. Contains a dual leucine-zipper motif, and has been shown to form dimers/oligomers through its leucine-zipper motif.
Protein type: Kinase, protein; EC 2.7.11.25; Protein kinase, TKL; Protein kinase, Ser/Thr (non-receptor); TKL group; MLK family; LZK subfamily
Chromosomal Location of Human Ortholog: 3q27
Cellular Component: IkappaB kinase complex; membrane
Molecular Function: identical protein binding; MAP kinase kinase kinase activity; protein binding; protein homodimerization activity; protein kinase binding; protein serine/threonine kinase activity
Biological Process: activation of MAPKK activity; activation of NF-kappaB transcription factor; JNK cascade; protein amino acid autophosphorylation; protein amino acid phosphorylation
Research Articles on MAP3K13
Similar Products
Product Notes
The MAP3K13 map3k13 (Catalog #AAA1277125) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGTCATTTG CTGGCACGGT CGCATGGATG GCGCCAGAGG TGATACGGAA TGAACCTGTC TCTGAAAAAG TTGATATATG GTCTTTTGGA GTGGTGCTTT GGGAGCTGCT GACAGGAGAG ATCCCTTACA AAGATGTAGA TTCTTCAGCC ATTATCTGGG GTGTTGGAAG CAACAGCCTC CACCTTCCAG TTCCTTCCAC TTGCCCTGAT GGATTCAAAA TCCTTATGAA ACAGACGTGG CAGAGTAAAC CTCGAAACCG ACCTTCTTTT CGGCAGACAC TCATGCATTT AGACATTGCC TCTGCAGATG TACTTGCCAC CCCACAAGAA ACTTACTTCA AGTCTCAGGC TGAATGGAGA GAAGAAGTGA AAAAACATTT TGAGAAGATC AAAAGTGAAG GAACTTGTAT ACACCGGTTA GATGAAGAAC TGATTCGAAG GCGCAGAGAA GAGCTCAGGC ATGCGCTGGA TATTCGTGAA CACTATGAGC GGAAGCTTGA GCGGGCGAAT AATTTATACA TGGAATTGAG TGCCATCATG CTGCAGCTAG AAATGCGGGA GAAGGAGCTC ATTAAGCGTG AGCAAGCAGT GGAAAAGAAG TATCCTGGGA CCTACAAACG ACACCCTGTT CGTCCTATCA TCCATCCCAA TGCCATGGAG AAACTCATGA AAAGGAAAGG AGTGCCTCAC AAATCTGGGA TGCAGACCAA ACGGCCAGAC TTGTTGAGAT CAGAAGGGAT CCCCACCACA GAAGTGGCTC CCACTGCATC CCCTTTGTCC GGAAGTCCCA AAATGTCCAC TTCTAGCAGC AAGAGCCGAT ATCGAAGCAA ACCACGCCAC CGCCGAGGGA ATAGCAGAGG CAGCCATAGT GACTTTGCCG CAATCTTGAA AAACCAGCCA GCCCAGGAAA ATTCACCCCA TCCCACTTAC CTGCACCAAG CTCAATCCCA ATACCCTTCT CTTCATCACC ATAATTCTCT GCAGCAGCAA TACCAGCAGC CCCCTCCTGC CATGTCCCAG AGTCACCATC CCAGACTCAA TATGCACGGA CAGGACATAG CAACCTGCGC CAACAACCTG AGGTATTTCG GCCCAGCAGC AGCCCTGCGG AGCCCACTCA GCAACCATGC TCAGAGACAG CTGCCCGGCT CGAGCCCTGA CCTCATCTCC ACAGCCATGG CTGCAGACTG CTGGAGAAGT TCTGAGCCTG ACAAGGGCCA AGCTGGTCCC TGGGGCTGTT GCCAGGCTGA CGCTTATGAC CCCTGCCTTC AGTGCAGGCC AGAACAGTAT GGGTCCTTAG ACATACCCTC TGCTGAGCCA GTGGGGAGGA GCCCTGACCT TTCCAAGTCA CCAGCACATA ATCCTCTCTT GGAAAACGCC CAGAGTTCTG AGAAAACGGA AGAAAATGAA TTCAGCGGCT GTAGGTCTGA GTCATCCCTC GGCACCTCTC ATCTCGGCAC CCCTCCAGCG CTACCTCGAA AAACAAGGCC TCTGCAGAAG AGTGGAGATG ACTCCTCAGA AGAGGAAGAA GGGGAAGTAG ATAGTGAAGT TGAATTTCCA CGAAGACAGA GGCCCCATCG CTGTATCAGC AGCTGCCAGT CATATTCAAC CTTTAGCTCT GAGAATTTCT CTGTGTCTGA TGGAGAAGAG GGAAATACCA GTGACCACTC AAACAGTCCT GATGAGTTAG CTGATAAACT TGAAGACCGC TTGGCAGAGA AGCTAGACGA CCTGCTGTCC CAGACGCCAG AGATTCCCAT TGACATATCC TCACACTCGG ATGGGCTCTC TGACAAGGAG TGTGCCGTGC GCCGTGTGAA GACTCAGATG TCTCTGGGCA AGCTGTGTGT GGAGGAACGT GGCTATGAGA ACCCCATGCA GTTTGAAGAA TCGGACTGTG ACTCTTCAGA TGGGGAGTGT TCTGATGCCA CAGTTAGGAC CAATAAACAC TACAGCTCTG CTACCTGGTA A. It is sometimes possible for the material contained within the vial of "MAP3K13, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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