EHMT2 cdna clone
EHMT2 cDNA Clone
Gene Names
EHMT2; G9A; BAT8; GAT8; NG36; KMT1C; C6orf30
Synonyms
EHMT2; EHMT2 cDNA Clone; EHMT2 cdna clone
Sequence
atgagtgatgatgtccactcactgggaaaggtgacctcagatctggccaaaaggaggaagctgaactcaggaggtggcctgtcggaggagttaggttctgcccggcgttcaggagaagtgaccctgacgaaaggggaccccgggtccctggaggagtgggagacggtggtgggtgatgacttcagtctctactatgattcctactctgtggatgagcgcgtggactccgacagcaagtctgaagttgaagctctaactgaacaactaagtgaagaggaggaggaggaagaggaggaagaagaagaagaggaagaggaggaggaagaggaagaagaagaggaagatgaggagtcagggaatcagtcagataggagtggttccagtggccggcgcaaggccaagaagaaatggcgaaaagacagcccatgggtgaagccgtctcggaaacggcgcaagcgggagcctccgcgggccaaggagccacgaggagtgaatggtgtgggctcctcaggccccagtgagtacatggaggtccctctggggtccctggagctgcccagcgaggggaccctctcccccaaccacgctggggtgtccaatgacacatcttcgctggagacagagcgagggtttgaggagttgcccctgtgcagctgccgcatggaggcacccaagattgaccgcatcagcgagagggcggggcacaagtgcatggccactgagagtgtggacggagagctgtcaggctgcaatgccgccatcctcaagcgggagaccatgaggccatccagccgtgtggccctgatggtgctctgtgagacccaccgcgcccgcatggtcaaacaccactgctgcccgggctgcggctacttctgcacggcgggcaccttcctggagtgccaccctgacttccgtgtggcccaccgcttccacaaggcctgtgtgtctcagctgaatgggatggtcttctgtccccactgtggggaggatgcttctgaagctcaagaggtgaccatcccccggggtgacggggtgaccccaccggccggcactgcagctcctgcacccccacccctgtcccaggatgtccccgggagagcagacacttctcagcccagtgcccggatgcgagggcatggggaaccccggcgcccgccctgcgatcccctggctgacaccattgacagctcagggccctccctgaccctgcccaatgggggctgcctttcagccgtggggctgccactggggccaggccgggaggccctggaaaaggccctggtcatccaggagtcagagaggcggaagaagctccgtttccaccctcggcagttgtacctgtccgtgaagcagggcgagctgcagaaggtgatcctgatgctgttggacaacctggaccccaacttccagagcgaccagcagagcaagcgcacgcccctgcatgcagccgcccagaagggctccgtggagatctgccatgtgctgctgcaggctggagccaacataaatgcagtggacaaacagcagcggacgccactgatggaggccgtggtgaacaaccacctggaggtagcccgttacatggtgcagcgtggtggctgtgtctatagcaaggaggaggacggttccacctgcctccaccacgcagccaaaatcgggaacttggagatggtcagcctgctgctgagcacaggacaggtggacgtcaacgcccaggacagtggggggtggacgcccatcatctgggctgcagagcacaagcacatcgaggtgatccgcatgctactgacgcggggcgccgacgtcaccctcactgacaacgaggagaacatctgcctgcactgggcctccttcacgggcagcgccgccatcgccgaagtccttctgaatgcgcgctgtgacctccatgctgtcaactaccatggggacacccccctgcacatcgcagctcgggagagctaccatgactgcgtgctgttattcctgtcacgtggggccaaccctgagctgcggaacaaagagggggacacagcatgggacctgactcccgagcgctccgacgtgtggtttgcgcttcaactcaaccgcaagctccgacttggggtgggaaatcgggccatccgcacagagaagatcatctgccgggacgtggctcggggctatgagaacgtgcccattccctgtgtcaacggtgtggatggggagccctgccctgaggattacaagtacatctcagagaactgcgagacgtccaccatgaacatcgatcgcaacatcacccacctgcagcactgcacgtgtgtggacgactgctctagctccaactgcctgtgcggccagctcagcatccggtgctggtatgacaaggatgggcgattgctccaggaatttaacaagattgagcctccgctgattttcgagtgtaaccaggcgtgctcatgctggagaaactgcaagaaccgggtcgtacagagtggcatcaaggtgcggctacagctctaccgaacagccaagatgggctggggggtccgcgccctgcagaccatcccacaggggaccttcatctgcgagtatgtcggggagctgatctctgatgctgaggctgatgtgagagaggatgattcttacctcttcgacttagacaacaaggatggagaggtgtactgcatagatgcccgttactatggcaacatcagccgcttcatcaaccacctgtgtgaccccaacatcattcccgtccgggtcttcatgctgcaccaagacctgcgatttccacgcatcgccttcttcagttcccgagacatccggactggggaggagctagggtttgactatggcgaccgcttctgggacatcaaaagcaaatatttcacctgccaatgtggctctgagaagtgcaagcactcagccgaagccattgccctggagcagagccgtctggcccgcctggacccacaccctgagctgctgcccgagctcggctccctgccccctgtcaacacatga
Sequence Length
3006
Vector
pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
19,864 Da
NCBI Official Full Name
Homo sapiens euchromatic histone-lysine N-methyltransferase 2, mRNA
NCBI Official Synonym Full Names
euchromatic histone lysine methyltransferase 2
NCBI Official Symbol
EHMT2
NCBI Official Synonym Symbols
G9A; BAT8; GAT8; NG36; KMT1C; C6orf30
NCBI Protein Information
histone-lysine N-methyltransferase EHMT2
UniProt Protein Name
Histone-lysine N-methyltransferase EHMT2
Protein Family
UniProt Gene Name
EHMT2
UniProt Synonym Gene Names
BAT8; C6orf30; G9A; KMT1C; NG36; H3-K9-HMTase 3
UniProt Entry Name
EHMT2_HUMAN
NCBI Description
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Uniprot Description
EHMT2 iso4: Histone methyltransferase. Preferentially methylates 'Lys-9' of histone H3 and 'Lys-27' of histone H3 (in vitro). H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. Also methylates histone H1. Belongs to the histone-lysine methyltransferase family. Suvar3-9 subfamily. Part of the E2F6.com-1 complex in G0 phase composed of E2F6, MGA, MAX, TFDP1, CBX3, BAT8, EUHMTASE1, RING1, RNF2, MBLR, L3MBTL2 and YAF2. Interacts with GFI1B, WIZ and EHMT1. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Amino Acid Metabolism - lysine degradation; EC 2.1.1.43; Methyltransferase; Methyltransferase, protein lysine
Chromosomal Location of Human Ortholog: 6p21.31
Cellular Component: nuclear chromatin; nucleoplasm; nucleus
Molecular Function: histone lysine N-methyltransferase activity (H3-K27 specific); histone lysine N-methyltransferase activity (H3-K9 specific); histone-lysine N-methyltransferase activity; p53 binding; protein binding; protein-lysine N-methyltransferase activity
Biological Process: cellular response to starvation; DNA methylation; histone methylation; negative regulation of transcription from RNA polymerase II promoter; peptidyl-lysine di-methylation; regulation of DNA replication
Research Articles on EHMT2
Similar Products
Product Notes
The EHMT2 ehmt2 (Catalog #AAA1277064) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgagtgatg atgtccactc actgggaaag gtgacctcag atctggccaa aaggaggaag ctgaactcag gaggtggcct gtcggaggag ttaggttctg cccggcgttc aggagaagtg accctgacga aaggggaccc cgggtccctg gaggagtggg agacggtggt gggtgatgac ttcagtctct actatgattc ctactctgtg gatgagcgcg tggactccga cagcaagtct gaagttgaag ctctaactga acaactaagt gaagaggagg aggaggaaga ggaggaagaa gaagaagagg aagaggagga ggaagaggaa gaagaagagg aagatgagga gtcagggaat cagtcagata ggagtggttc cagtggccgg cgcaaggcca agaagaaatg gcgaaaagac agcccatggg tgaagccgtc tcggaaacgg cgcaagcggg agcctccgcg ggccaaggag ccacgaggag tgaatggtgt gggctcctca ggccccagtg agtacatgga ggtccctctg gggtccctgg agctgcccag cgaggggacc ctctccccca accacgctgg ggtgtccaat gacacatctt cgctggagac agagcgaggg tttgaggagt tgcccctgtg cagctgccgc atggaggcac ccaagattga ccgcatcagc gagagggcgg ggcacaagtg catggccact gagagtgtgg acggagagct gtcaggctgc aatgccgcca tcctcaagcg ggagaccatg aggccatcca gccgtgtggc cctgatggtg ctctgtgaga cccaccgcgc ccgcatggtc aaacaccact gctgcccggg ctgcggctac ttctgcacgg cgggcacctt cctggagtgc caccctgact tccgtgtggc ccaccgcttc cacaaggcct gtgtgtctca gctgaatggg atggtcttct gtccccactg tggggaggat gcttctgaag ctcaagaggt gaccatcccc cggggtgacg gggtgacccc accggccggc actgcagctc ctgcaccccc acccctgtcc caggatgtcc ccgggagagc agacacttct cagcccagtg cccggatgcg agggcatggg gaaccccggc gcccgccctg cgatcccctg gctgacacca ttgacagctc agggccctcc ctgaccctgc ccaatggggg ctgcctttca gccgtggggc tgccactggg gccaggccgg gaggccctgg aaaaggccct ggtcatccag gagtcagaga ggcggaagaa gctccgtttc caccctcggc agttgtacct gtccgtgaag cagggcgagc tgcagaaggt gatcctgatg ctgttggaca acctggaccc caacttccag agcgaccagc agagcaagcg cacgcccctg catgcagccg cccagaaggg ctccgtggag atctgccatg tgctgctgca ggctggagcc aacataaatg cagtggacaa acagcagcgg acgccactga tggaggccgt ggtgaacaac cacctggagg tagcccgtta catggtgcag cgtggtggct gtgtctatag caaggaggag gacggttcca cctgcctcca ccacgcagcc aaaatcggga acttggagat ggtcagcctg ctgctgagca caggacaggt ggacgtcaac gcccaggaca gtggggggtg gacgcccatc atctgggctg cagagcacaa gcacatcgag gtgatccgca tgctactgac gcggggcgcc gacgtcaccc tcactgacaa cgaggagaac atctgcctgc actgggcctc cttcacgggc agcgccgcca tcgccgaagt ccttctgaat gcgcgctgtg acctccatgc tgtcaactac catggggaca cccccctgca catcgcagct cgggagagct accatgactg cgtgctgtta ttcctgtcac gtggggccaa ccctgagctg cggaacaaag agggggacac agcatgggac ctgactcccg agcgctccga cgtgtggttt gcgcttcaac tcaaccgcaa gctccgactt ggggtgggaa atcgggccat ccgcacagag aagatcatct gccgggacgt ggctcggggc tatgagaacg tgcccattcc ctgtgtcaac ggtgtggatg gggagccctg ccctgaggat tacaagtaca tctcagagaa ctgcgagacg tccaccatga acatcgatcg caacatcacc cacctgcagc actgcacgtg tgtggacgac tgctctagct ccaactgcct gtgcggccag ctcagcatcc ggtgctggta tgacaaggat gggcgattgc tccaggaatt taacaagatt gagcctccgc tgattttcga gtgtaaccag gcgtgctcat gctggagaaa ctgcaagaac cgggtcgtac agagtggcat caaggtgcgg ctacagctct accgaacagc caagatgggc tggggggtcc gcgccctgca gaccatccca caggggacct tcatctgcga gtatgtcggg gagctgatct ctgatgctga ggctgatgtg agagaggatg attcttacct cttcgactta gacaacaagg atggagaggt gtactgcata gatgcccgtt actatggcaa catcagccgc ttcatcaacc acctgtgtga ccccaacatc attcccgtcc gggtcttcat gctgcaccaa gacctgcgat ttccacgcat cgccttcttc agttcccgag acatccggac tggggaggag ctagggtttg actatggcga ccgcttctgg gacatcaaaa gcaaatattt cacctgccaa tgtggctctg agaagtgcaa gcactcagcc gaagccattg ccctggagca gagccgtctg gcccgcctgg acccacaccc tgagctgctg cccgagctcg gctccctgcc ccctgtcaac acatga. It is sometimes possible for the material contained within the vial of "EHMT2, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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