C7 cdna clone
C7 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection. [provided by RefSeq, Jul 2008]
Uniprot Description
C7: Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor. Defects in C7 are a cause of complement component 7 deficiency (C7D). A rare defect of the complement classical pathway associated with susceptibility to severe recurrent infections, predominantly by Neisseria gonorrhoeae or Neisseria meningitidis. Belongs to the complement C6/C7/C8/C9 family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 5p13
Cellular Component: extracellular region
Biological Process: complement activation; regulation of complement activation
Disease: Complement Component 7 Deficiency
Research Articles on C7
Similar Products
Product Notes
The C7 c7 (Catalog #AAA1277039) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgaaggtga taagcttatt cattttggtg ggatttatag gagagttcca aagtttttca agtgcctcct ctccagtcaa ctgccagtgg gacttctatg ccccttggtc agaatgcaat ggctgtacca agactcagac tcgcaggcgg tcagttgctg tgtatgggca gtatggaggc cagccttgtg ttggaaatgc ttttgaaaca cagtcctgtg aacctacaag aggatgtcca acagaggagg gatgtggaga gcgtttcagg tgcttttcag gtcagtgcat cagcaaatca ttggtttgca atggggattc tgactgtgat gaagacagtg ctgatgaaga cagatgtgag gactcagaaa ggagaccttc ctgtgatatc gataaacctc ctcctaacat agaacttact ggaaatggtt acaatgaact cactggccag tttaggaaca gagtcatcaa taccaaaagt tttggtggtc aatgtagaaa ggtgtttagt ggggatggaa aagatttcta caggctgagt ggaaatgtcc tgtcctatac attccaggtg aaaataaata atgattttaa ttatgaattt tacaatagta cttggtctta tgtaaaacat acgtcgacag aacacacatc atctagtcgg aagcgctcct tttttagatc ttcatcatct tcttcacgca gttatacttc acataccaat gaaatccata aaggaaagag ttaccaactg ctggttgttg agaacactgt tgaagtggct cagttcatta ataacaatcc agaattttta caacttgctg agccattctg gaaggagctt tcccacctcc cctctctgta tgactacagt gcctaccgaa gattaatcga ccagtacggg acacattatc tgcaatctgg gtcgttagga ggagaataca gagttctatt ttatgtggac tcagaaaaat taaaacaaaa tgattttaat tcagtcgaag aaaagaaatg taaatcctca ggttggcatt ttgtcgttaa attttcaagt catggatgca aggaactgga aaacgcttta aaagctgctt caggaaccca gaacaatgta ttgcgaggag aaccgttcat cagaggggga ggtgcaggct tcatatctgg ccttagttac ctagagctgg acaatcctgc tggaaacaaa aggcgatatt ctgcctgggc agaatctgtg actaatcttc ctcaagtcat aaaacaaaag ctgacacctt tatatgagct ggtaaaggaa gtaccttgtg cctctgtgaa aaaactatac ctgaaatggg ctcttgaaga gtatctggat gaatttgacc cctgtcattg ccggccttgt caaaatggtg gtttggctac tgttgagggg acccattgtc tgtgccattg caaaccgtac acatttggtg cggcgtgtga gcaaggagtc ctcgtaggga atcaagcagg aggggttgat ggaggttgga gttgctggtc ctcttggagc ccctgtgtcc aagggaagaa aacaagaagc cgtgaatgca ataacccacc tcccagtggg ggtgggagat cctgcgttgg agaaacgaca gaaagcacac aatgcgaaga tgaggagctg gagcacttga ggttgcttga accacattgc tttcctttgt ctttggttcc aacagaattc tgtccatcac ctcctgcctt gaaagatgga tttgttcaag atgaaggtac aatgtttcct gtggggaaaa atgtagtgta cacttgcaat gaaggatact ctcttattgg aaacccagtg gccagatgtg gagaagattt acggtggctt gttggggaaa tgcattgtca gaaaattgcc tgtgttctac ctgtactgat ggatggcata cagagtcacc cccaaaaacc tttctacaca gttggtgaga aggtgactgt ttcctgttca ggtggcatgt ccttagaagg tccttcagca tttctctgtg gctccagcct taagtggagt cctgagatga agaatgcccg ctgtgtacaa aaagaaaatc cgttaacaca ggcagtgcct aaatgtcagc gctgggagaa actgcagaat tcaagatgtg tttgtaaaat gccctacgaa tgtggacctt ccttggatgt atgtgctcaa gatgagagaa gcaaaaggat actgcctctg acagtttgca agatgcatgt tctccactgt cagggtagaa attacaccct tactggtagg gacagctgta ctctgcctgc ctcagctgag aaagcttgtg gtgcctgccc actgtgggga aaatgtgatg ctgagagcag caaatgtgtc tgccgagaag catcggagtg cgaggaagaa gggtttagca tttgtgtgga agtgaacggc aaggagcaga cgatgtctga gtgtgaggcg ggcgctctga gatgcagagg gcagagcatc tctgtcacca gcataaggcc ttgtgctgcg gaaacccagt ag. It is sometimes possible for the material contained within the vial of "C7, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.