RNF38 cdna clone
RNF38 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with a coiled-coil motif and a RING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is a zinc-binding domain found in a large set of proteins playing roles in diverse cellular processes including oncogenesis, development, signal transduction, and apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Uniprot Description
RNF38: 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 9p13
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: ubiquitin-protein ligase activity
Biological Process: proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; regulation of transcription, DNA-dependent