CPSF6 cdna clone
CPSF6 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins. [provided by RefSeq, Jul 2008]
Uniprot Description
CPSF6: Component of the cleavage factor Im complex (CFIm) that plays a key role in pre-mRNA 3'-processing. Involved in association with NUDT21/CPSF5 in pre-MRNA 3'-end poly(A) site cleavage and poly(A) addition. CPSF6 binds to cleavage and polyadenylation RNA substrates and promotes RNA looping. Belongs to the RRM CPSF6/7 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA-binding; Spliceosome; RNA processing
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: membrane; mRNA cleavage factor complex; nucleoplasm; nucleus; paraspeckles; ribonucleoprotein complex
Molecular Function: mRNA binding; protein binding; RNA binding
Biological Process: mRNA polyadenylation; mRNA processing; protein tetramerization
Research Articles on CPSF6
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Product Notes
The CPSF6 cpsf6 (Catalog #AAA1276795) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcggacg gcgtggacca catagacatt tacgcggatg tcggcgaaga gttcaaccag gaagctgaat atggtgggca tgatcagata gatttgtatg acgatgtcat atctccatct gcaaataatg gagatgcccc agaagaccga gattacatgg atactctccc accaactgtt ggtgatgatg tgggtaaagg agcagcacca aatgttgtct atacatatac tggaaagaga attgcattat atattggaaa tctaacatgg tggacaacag atgaagactt aactgaagca gttcattctt tgggagtaaa tgatattttg gagataaaat tttttgaaaa tcgagcaaat ggccagtcaa aggggtttgc ccttgttggt gttggatctg aagcatcttc aaaaaagtta atggatctgt tacctaaaag agaacttcat ggtcagaatc ctgttgtaac tccatgcaat aaacagttcc tgagtcaatt tgaaatgcag tccaggaaaa ctacacaatc aggacaaatg tctggggaag gtaaagctgg tcctcctcta gctgggcctc ctaatcgagg agatcgccct ccaccaccag ttctttttcc tggacaacct tttgggcagc ctccattggg tccacttcct cctggccctc cacctccagt tccaggctac ggcccccctc ctggcccacc acctccacaa cagggaccac ctccacctcc aggccccttt ccacctcgtc cacccggtcc acttgggcca ccccttacac tagctcctcc tccgcatctt cctggaccac ctccaggtgc cccaccgcca gctccgcatg tgaacccagc tttctttcct ccaccaacta acagtggcat gcctacatca gatagccgag gtccaccacc aacagatcca tatgggcgac ctccaccata tgataggggt gactatggcc cccctggaag ggaaatggat actgcaagaa cgccattgag tgaagctgaa tttgaagaaa tcatgaatag aaatagggca atctcaagca gtgctatttc gagagctgtg tctgatgcca gtgctggtga ttatgggagt gctattgaga cactggtaac tgcaatttct ttaattaaac aatccaaagt atctgctgat gatcgttgca aagttcttat tagttctttg caagattgcc ttcatggaat tgagtccaag tcttatggtt ctggatcaag acgtgaacga tcaagagaga gggaccatag tagatcacga gaaaagagtc gacgtcataa atcccgtagt agagaccgtc atgacgatta ttacagagag agaagcagag aacgagagag gcaccgggat cgtgaccgag accgtgaccg agagcgtgac cgagagcgcg aatatcgtca tcgttag. It is sometimes possible for the material contained within the vial of "CPSF6, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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