RERG cdna clone
RERG cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]
Uniprot Description
RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric
Chromosomal Location of Human Ortholog: 12p12.3
Cellular Component: cytosol; nucleus
Molecular Function: GDP binding; GTPase activity
Biological Process: negative regulation of cell growth; negative regulation of cell proliferation; response to hormone stimulus
Research Articles on RERG
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Product Notes
The RERG rerg (Catalog #AAA1276566) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctaaaa gtgcggaggt caaactggca atatttggga gagcaggcgt gggcaagtca gctcttgtag tgagatttct gaccaaacgg ttcatctggg aatatgatcc caccctcgaa tcaacctacc gacaccaagc aaccatcgat gatgaagttg tttccatgga gatactagac actgctggtc aggaagatac cattcagagg gaggggcaca tgcgatgggg ggaaggcttt gtgctggtct acgacattac tgaccgagga agttttgagg aagtgctgcc acttaagaac atcctagatg agatcaaaaa gcccaagaat gtgactctca tcttggttgg aaacaaagct gacttggacc actccaggca ggttagcaca gaagaaggag agaagctggc cacagaattg gcttgtgctt tttacgagtg ctctgcctgc actggagaag ggaacatcac agagatattc tatgaattgt gtcgagaggt gcgtcgccgg aggatggtgc agggcaagac gaggcgacgc agctccacca cgcatgtcaa gcaagccatt aacaagatgc tcaccaaaat cagtagttag. It is sometimes possible for the material contained within the vial of "RERG, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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