Rabbit anti-Human, Mouse RERG Polyclonal Antibody | anti-RERG antibody

RERG Rabbit Polyclonal

Cat. Num. AAA7603476

• Reactivity: Human, Mouse
• Applications: ELISA, Western Blot, Immunohistochemistry
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: RERG; Polyclonal Antibody; RERG Rabbit Polyclonal; anti-RERG antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 199

• Applicable Applications for anti-RERG antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Immunogen: RAS-like, estrogen-regulated, growth inhibitor
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human breast cancer using MBS7603476 (RERG antibody) at dilution of 1:50)

Western Blot (WB)

(MCF7 cells were subjected to SDS PAGE followed by western blot with MBS7603476 (RERG antibody) at dilution of 1:1000)

NCBI and Uniprot Product Information

• NCBI GI #: 14249704
• NCBI GeneID: 85004
• NCBI Accession #: NP_116307.1
• NCBI GenBank Nucleotide #: NM_032918.2
• Molecular Weight: 20,258 Da
• NCBI Official Full Name: ras-related and estrogen-regulated growth inhibitor isoform 1
• NCBI Official Synonym Full Names: RAS like estrogen regulated growth inhibitor
• NCBI Official Symbol: RERG
• NCBI Protein Information: ras-related and estrogen-regulated growth inhibitor
• UniProt Protein Name: Ras-related and estrogen-regulated growth inhibitor
• Protein Family: Ras-related and estrogen-regulated growth inhibitor
• UniProt Gene Name: RERG
• UniProt Entry Name: RERG_HUMAN

NCBI Description

RERG, a member of the RAS superfamily of GTPases, inhibits cell proliferation and tumor formation (Finlin et al., 2001 [PubMed 11533059]).[supplied by OMIM, Mar 2009]

Uniprot Description

RERG: Binds GDP/GTP and possesses intrinsic GTPase activity. Has higher affinity for GDP than for GTP. In cell lines overexpression leads to a reduction in the rate of proliferation, colony formation and in tumorigenic potential. Belongs to the small GTPase superfamily. Ras family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: G protein, monomeric, Ras; G protein; G protein, monomeric

Chromosomal Location of Human Ortholog: 12p12.3

Cellular Component: cytosol; membrane; nucleus

Molecular Function: estrogen receptor binding; GDP binding; GTP binding; GTPase activity

Biological Process: negative regulation of cell growth; negative regulation of cell proliferation; protein transport; response to hormone stimulus; small GTPase mediated signal transduction