PLK4 cdna clone
PLK4 cDNA Clone
Gene Names
PLK4; SAK; STK18; MCCRP2
Synonyms
PLK4; PLK4 cDNA Clone; PLK4 cdna clone
Sequence
atggcgacctgcatcggggagaagatcgaggattttaaagttggaaatctgcttggtaaaggatcatttgctggtgtctacagagctgagtccattcacactggtttggaagttgcaatcaaaatgatagataagaaagccatgtacaaagcaggaatggtacagagagtccaaaatgaggtgaaaatacattgccaattgaaacatccttctatcttggagctttataactattttgaagatagcaattatgtgtatctggtattagaaatgtgccataatggagaaatgaacaggtatctaaagaatagagtgaaacccttctcagaaaatgaagctcgacacttcatgcaccagatcatcacagggatgttgtatcttcattctcatggtatactacaccgggacctcacactttctaacctcctactgactcgtaatatgaacatcaagattgctgattttgggctggcaactcaactgaaaatgccacatgaaaagcactatacattatgtggaactcctaactacatttcaccagaaattgccactcgaagtgcacatggccttgaatctgatgtttggtccctgggctgtatgttttatacattacttatcgggagaccacccttcgacactgacacagtcaagaacacattaaataaagtagtattggcagattatgaaatgccatcttttttgtcaatagaggccaaggaccttattcaccagttacttcgtagaaatccagcagatcgtttaagtctgtcttcagtattggaccatccttttatgtcccgaaattcttcaacaaaaagtaaagatttaggaactgtggaagactcaattgatagtgggcatgccacaatttctactgcaattacagcttcttccagtaccagtataagtggtagtttatttgacaaaagaagacttttgattggtcagccactcccaaataaaatgactgtatttccaaagaataaaagttcaactgatttttcttcttcaggagatggaaacagtttttatactcagtggggaaatcaagaaaccagtaatagtggaaggggaagagtaattcaagatgcagaagaaaggccacattctcgataccttcgtagagcttattcctctgatagatctggcacttctaatagtcagtctcaagcaaaaacatatacaatggaacgatgtcactcagcagaaatgctttcagtgtccaaaagatcaggaggaggtgaaaatgaagagaggtactcacccacagacaacaatgccaacatttttaacttctttaaagaaaagacatccagtagttctggatcttttgaaagacctgataacaatcaagcactctccaatcatctttgtccaggaaaaactccttttccatttgcagacccgacacctcagactgaaaccgtacaacagtggtttgggaatctgcaaataaatgctcatttaagaaaaactactgaatatgacagcatcagcccaaaccgggacttccagggccatccagatttgcagaaggacacatcaaaaaatgcctggactgatacaaaagtcaaaaagaactctgatgcttctgataatgcacattctgtaaaacagcaaaataccatgaaatatatgactgcacttcacagtaaacctgagataatccaacaagaatgtgtttttggctcagatcctctttctgaacagagcaagactaggggtatggagccaccatggggttatcagaatcgtacattaagaagcattacatctccgttggttgctcacaggttaaaaccaatcagacagaaaaccaaaaaggctgtggtgagcatacttgattcagaggaggtgtgtgtggagcttgtaaaggagtatgcatctcaagaatatgtgaaagaagttcttcagatatctagtgatggaaatacgatcactatttattatccaaatggtggtagaggttttcctcttgctgatagaccaccctcacctactgacaacatcagtaggtacagctttgacaatttaccagaaaaatactggcgaaaatatcaatatgcttccaggtttgtacagcttgtaagatctaaatctcccaaaatcacttattttacaagatatgctaaatgcattttgatggagaattctcctggtgctgattttgaggtttggttttatgatggggtaaaaatacacaaaacagaagatttcattcaggtgattgaaaagacagggaagtcttacactttaaaaagtgaaagtgaagttaatagcttgaaagaggagataaaaatgtatatggaccatgctaatgagggtcatcgtatttgtttagcactggaatccataatttcagaagaggaaaggaaaactaggagtgctccctttttcccaataatcataggaagaaaacctggtagtactagttcacctaaggccttatcacctcctccttctgtggattcaaattacccaacgagagagagagcatctttcaacagaatggtcatgcatagtgctgcttctccaacacaggcaccaatccttaatccctctatggttacaaatgaaggacttggtcttacaactacagcttctggaacagacatctcttctaatagtctaaaagattgtcttcctaaatcagcacaacttttgaaatctgtttttgtgaaaaatgttggttgggctacacagttaactagtggagctgtgtgggttcagtttaatgatgggtcccagttggttgtgcaggcaggagtgtcttctatcagttatacctcaccaaatggtcaaacaactaggtatggagaaaatgaaaaattaccagactacatcaaacagaaattacagtgtctgtcttccatccttttgatgttttctaatccgactcctaattttcattga
Sequence Length
2913
Vector
Please Inquire
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
104,636 Da
NCBI Official Full Name
Homo sapiens polo-like kinase 4 (Drosophila), mRNA
NCBI Official Synonym Full Names
polo like kinase 4
NCBI Official Symbol
PLK4
NCBI Official Synonym Symbols
SAK; STK18; MCCRP2
NCBI Protein Information
serine/threonine-protein kinase PLK4
UniProt Protein Name
Serine/threonine-protein kinase PLK4
UniProt Gene Name
PLK4
UniProt Synonym Gene Names
SAK; STK18; PLK-4
UniProt Entry Name
PLK4_HUMAN
NCBI Description
This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
Uniprot Description
PLK4: a kinase of the PLK family. Localizes to centrosomes and the cleavage furrow during cytokinesis. Interacts with the protein kinase Tec.
Protein type: Protein kinase, Other; Nucleolus; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.21; Kinase, protein; Other group; PLK family
Chromosomal Location of Human Ortholog: 4q28
Cellular Component: centriole; centrosome; cytosol; nucleolus
Molecular Function: identical protein binding; protein binding; protein serine/threonine kinase activity
Biological Process: centriole replication; G2/M transition of mitotic cell cycle; positive regulation of centriole replication
Disease: Microcephaly And Chorioretinopathy, Autosomal Recessive, 2
Research Articles on PLK4
Similar Products
Product Notes
The PLK4 plk4 (Catalog #AAA1276485) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggcgacct gcatcgggga gaagatcgag gattttaaag ttggaaatct gcttggtaaa ggatcatttg ctggtgtcta cagagctgag tccattcaca ctggtttgga agttgcaatc aaaatgatag ataagaaagc catgtacaaa gcaggaatgg tacagagagt ccaaaatgag gtgaaaatac attgccaatt gaaacatcct tctatcttgg agctttataa ctattttgaa gatagcaatt atgtgtatct ggtattagaa atgtgccata atggagaaat gaacaggtat ctaaagaata gagtgaaacc cttctcagaa aatgaagctc gacacttcat gcaccagatc atcacaggga tgttgtatct tcattctcat ggtatactac accgggacct cacactttct aacctcctac tgactcgtaa tatgaacatc aagattgctg attttgggct ggcaactcaa ctgaaaatgc cacatgaaaa gcactataca ttatgtggaa ctcctaacta catttcacca gaaattgcca ctcgaagtgc acatggcctt gaatctgatg tttggtccct gggctgtatg ttttatacat tacttatcgg gagaccaccc ttcgacactg acacagtcaa gaacacatta aataaagtag tattggcaga ttatgaaatg ccatcttttt tgtcaataga ggccaaggac cttattcacc agttacttcg tagaaatcca gcagatcgtt taagtctgtc ttcagtattg gaccatcctt ttatgtcccg aaattcttca acaaaaagta aagatttagg aactgtggaa gactcaattg atagtgggca tgccacaatt tctactgcaa ttacagcttc ttccagtacc agtataagtg gtagtttatt tgacaaaaga agacttttga ttggtcagcc actcccaaat aaaatgactg tatttccaaa gaataaaagt tcaactgatt tttcttcttc aggagatgga aacagttttt atactcagtg gggaaatcaa gaaaccagta atagtggaag gggaagagta attcaagatg cagaagaaag gccacattct cgataccttc gtagagctta ttcctctgat agatctggca cttctaatag tcagtctcaa gcaaaaacat atacaatgga acgatgtcac tcagcagaaa tgctttcagt gtccaaaaga tcaggaggag gtgaaaatga agagaggtac tcacccacag acaacaatgc caacattttt aacttcttta aagaaaagac atccagtagt tctggatctt ttgaaagacc tgataacaat caagcactct ccaatcatct ttgtccagga aaaactcctt ttccatttgc agacccgaca cctcagactg aaaccgtaca acagtggttt gggaatctgc aaataaatgc tcatttaaga aaaactactg aatatgacag catcagccca aaccgggact tccagggcca tccagatttg cagaaggaca catcaaaaaa tgcctggact gatacaaaag tcaaaaagaa ctctgatgct tctgataatg cacattctgt aaaacagcaa aataccatga aatatatgac tgcacttcac agtaaacctg agataatcca acaagaatgt gtttttggct cagatcctct ttctgaacag agcaagacta ggggtatgga gccaccatgg ggttatcaga atcgtacatt aagaagcatt acatctccgt tggttgctca caggttaaaa ccaatcagac agaaaaccaa aaaggctgtg gtgagcatac ttgattcaga ggaggtgtgt gtggagcttg taaaggagta tgcatctcaa gaatatgtga aagaagttct tcagatatct agtgatggaa atacgatcac tatttattat ccaaatggtg gtagaggttt tcctcttgct gatagaccac cctcacctac tgacaacatc agtaggtaca gctttgacaa tttaccagaa aaatactggc gaaaatatca atatgcttcc aggtttgtac agcttgtaag atctaaatct cccaaaatca cttattttac aagatatgct aaatgcattt tgatggagaa ttctcctggt gctgattttg aggtttggtt ttatgatggg gtaaaaatac acaaaacaga agatttcatt caggtgattg aaaagacagg gaagtcttac actttaaaaa gtgaaagtga agttaatagc ttgaaagagg agataaaaat gtatatggac catgctaatg agggtcatcg tatttgttta gcactggaat ccataatttc agaagaggaa aggaaaacta ggagtgctcc ctttttccca ataatcatag gaagaaaacc tggtagtact agttcaccta aggccttatc acctcctcct tctgtggatt caaattaccc aacgagagag agagcatctt tcaacagaat ggtcatgcat agtgctgctt ctccaacaca ggcaccaatc cttaatccct ctatggttac aaatgaagga cttggtctta caactacagc ttctggaaca gacatctctt ctaatagtct aaaagattgt cttcctaaat cagcacaact tttgaaatct gtttttgtga aaaatgttgg ttgggctaca cagttaacta gtggagctgt gtgggttcag tttaatgatg ggtcccagtt ggttgtgcag gcaggagtgt cttctatcag ttatacctca ccaaatggtc aaacaactag gtatggagaa aatgaaaaat taccagacta catcaaacag aaattacagt gtctgtcttc catccttttg atgttttcta atccgactcc taattttcat tga. It is sometimes possible for the material contained within the vial of "PLK4, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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