SH3GL1 cdna clone
SH3GL1 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Uniprot Description
SH3GL1: Implicated in endocytosis. May recruit other proteins to membranes with high curvature. In some cases of acute leukemia, a translocation results in the formation of a MLL-EEN fusion gene. Belongs to the endophilin family.
Protein type: Vesicle; Oncoprotein
Chromosomal Location of Human Ortholog: 19p13.3
Cellular Component: cell-cell adherens junction; cytoplasm
Molecular Function: identical protein binding; protein binding
Biological Process: central nervous system development; signal transduction
Disease: Leukemia, Acute Myeloid
Research Articles on SH3GL1
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Product Notes
The SH3GL1 sh3gl1 (Catalog #AAA1276416) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atgtcggtgg cggggctgaa gaagcagttc tacaaggcga gccagctggt cagtgagaag gtcggagggg ccgaggggac caagctggat gatgacttca aagagatgga gaagaaggtg gatgtcacca gcaaggcggt gacagaagtg ctggccagga ccatcgagta cctgcagccc aacccagcct cgcgggctaa gctgaccatg ctcaacacgg tgtccaagat ccggggccag gtgaagaacc ccggctaccc gcagtcggag gggcttctgg gcgagtgcat gatccgccac gggaaggagc tgggcggcga gtccaacttt ggtgacgcat tgctggatgc cggcgagtcc atgaagcgcc tggcagaggt gaaggactcc ctggacatcg aggtcaagca gaacttcatt gaccccctcc agaacctgtg cgagaaagac ctgaaggaga tccagcacca cctgaagaaa ctggagggcc gccgcctgga ctttgactac aagaagaagc ggcagggcaa gatccccgat gaggagctac gccaggcgct ggagaagttc gaggagtcca aggaggtggc agaaaccagc atgcacaacc tcctggagac tgacatcgag caggtgagtc agctctcggc cctggtggat gcacagctgg actaccaccg gcaggccgtg cagatcctgg acgagctggc ggagaagctc aagcgcagga tgcgggaagc ttcctcacgc cctaagcggg agtataagcc gaagccccgg gagccctttg accttggaga gcctgagcag tccaacgggg gcttcccctg caccacagcc cccaagatcg cagcttcatc gtctttccga tcttccgaca agcccatccg gacccctagc cggagcatgc cgcccctgga ccagccgagc tgcaaggcgc tgtacgactt cgagcccgag aacgacgggg agctgggctt ccatgagggc gacgtcatca cgctgaccaa ccagatcgat gagaactggt acgagggcat gctggacggc cagtcgggct tcttcccgct cagctacgtg gaggtgcttg tgcccctgcc gcagtga. It is sometimes possible for the material contained within the vial of "SH3GL1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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