MRPL47 cdna clone
MRPL47 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq, Jul 2008]
Uniprot Description
MRPL47: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene is immediately adjacent to the gene for BAF complex 53 kDa subunit protein a (BAF53a), in a tail-to-tail orientation. Two transcript variants encoding different protein isoforms have been identified. [provided by RefSeq, Jul 2008]
Protein type: Translation; Mitochondrial; Ribosomal
Chromosomal Location of Human Ortholog: 3q26.33
Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit; mitochondrion
Molecular Function: structural constituent of ribosome
Biological Process: mitochondrial translation
Research Articles on MRPL47
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Product Notes
The MRPL47 mrpl47 (Catalog #AAA1273755) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggctgcgg ccggtttggc ccttctttgt aggagagttt catccgccct gaaatcttcc cgatcgttaa taactcctca ggtccctgcc tgcacaggat tacttcatac cacattgtca aggaaaggac tagaagaatt ttttgatgac ccaaaaaact gggggcaaga aaaagtaaaa tctggagcag catggacctg tcagcaacta aggaacaaaa gtaatgaaga tttacacaaa ctttggtatg tcttactgaa agaaagaaac atgcttctaa ccctagagca ggaggccaag cggcagagat tgccaatgcc aagtccagag cggttagata aggtagtaga ttccatggat gcattagata aagttgtcca ggaaagagaa gatgccctaa ggcttcttca gactggtcaa gaaagagcta gacctggtgc ttggagaaga gacatctttg gaagaatcat ctggcacaag ttcaagcagt gggttatacc ttggcaccta aataaaagat acaataggaa acgattcttt gccttgcctt atgtggacca ttttctcaga ctggaacgtg agaaacgagc ccgcatcaaa gcacggaagg aaaatttaga gagaaagaaa gcaaaaattc ttttaaaaaa gtttccacat cttgctgaag cccaaaagtc aagtcttgtc taa. It is sometimes possible for the material contained within the vial of "MRPL47, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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