SNX27 cdna clone
SNX27 cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the sorting nexin family, a diverse group of cytoplasmic and membrane-associated proteins involved in endocytosis of plasma membrane receptors and protein trafficking through these compartments. All members of this protein family contain a phosphoinositide binding domain (PX domain). A highly similar protein in mouse is responsible for the specific recruitment of an isoform of serotonin 5-hydroxytryptamine 4 receptor into early endosomes, suggesting the analogous role for the human protein. [provided by RefSeq, Jul 2008]
Uniprot Description
SNX27: Involved in endocytic trafficking. In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes. Belongs to the sorting nexin family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component: cytoplasm; early endosome; immunological synapse; nucleoplasm; retromer complex
Molecular Function: phosphatidylinositol 3-phosphate binding; protein binding
Biological Process: endosome transport; establishment of natural killer cell polarity; intracellular protein transport
Research Articles on SNX27
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Product Notes
The SNX27 snx27 (Catalog #AAA1273652) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: atggacagta cgacagtgaa ttactttgcc ttatttgaag tgatcagtca ctcctttgta cgtaaattgg cacctaatga gtttcctcac aaactctaca ttcagaatta tacatcagct gtgccaggca cctgcttgac cattcgaaag tggcttttta caacagaaga agaaattctc ttaaatgaca atgaccttgc tgttacctac ttctttcatc aggcagtcga tgatgtgaag aaaggttaca tcaaagcaga agaaaagtcc tatcaattac agaagctata cgaacaaaga aaaatggtca tgtacctcaa catgctaagg acttgtgagg gctacaatga aatcatcttt ccccactgtg cctgtgactc caggaggaag gggcacgtta tcacagccat cagcatcacg cactttaaac tgcatgcctg cactgaagaa ggacagctgg agaaccaggt aattgcattt gaatgggatg agatgcagcg atgggacaca gatgaagaag ggatggcctt ctgtttcgaa tatgcacgag gagagaagaa gccccgatgg gttaaaatct tcacgccata tttcaattac atgcatgagt gcttcgagag ggtgttctgc gagctcaagt ggagaaaaga ggaatattag. It is sometimes possible for the material contained within the vial of "SNX27, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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