KLHL21 cdna clone
KLHL21 cDNA Clone
Synonyms
KLHL21; KLHL21 cDNA Clone; KLHL21 cdna clone
Sequence
ATGGAGCGACCGGCGCCCCTGGCCGTGCTTCCCTTCTCGGACCCCGCGCACGCCCTGAGCCTGCTGCGCGGCCTGAGCCAGCTGCGCGCCGAGCGCAAGTTCCTGGACGTGACCCTGGAGGCGGCGGGCGGGCGCGACTTCCCGGCGCACCGTGCGGTGCTGGCCGCCGCCAGCCCCTACTTCCGCGCCATGTTCGCGGGGCAGCTGCGCGAGAGCCGCGCCGAGCGGGTGCGCCTGCACGGAGTGCCTCCCGACATGCTGCAGCTGCTGCTGGACTTCAGCTACACGGGCCGCGTGGCGGTAAGCGGCGACAACGCTGAGCCGCTGCTGCGCGCCGCCGACCTGCTGCAGTTCCCGGCCGTGAAGGAGGCGTGCGGGGCCTTCCTGCAGCAGCAGCTCGACCTGGCCAACTGCCTGGACATGCAGGACTTCGCTGAGGCCTTCAGCTGCTCGGGACTGGCGAGCGCGGCGCAGCGGTTCATTCTGCGCCACGTGGGCGAGCTGGGCGCCGAGCAGCTGGAGCGGCTGCCACTGGCGCGCCTGCTGCGCTACCTGCGGGACGACGGGCTGTGTGTGCCCAAGGAGGAGGCCGCCTACCAGCTGGCGCTGCGCTGGGTCCGCGCTGACCCGCCGCGCCGCGCCGCGCACTGGCCGCAGCTGCTGGAGGCCGTGCGCCTGCCCTTCGTGCGCCGCTTCTACCTGTTGGCGCACGTCGAGGCCGAGCCGCTGGTGGCGCGCTGCCCACCCTGCCTGCGCCTGCTGCGCGAGGCGCGCGACTTCCAGGCGGCGCGCTACGACCGCCACGACCGCGGGCCCTGTCCCCGAATGCGTCCTCGCCCGTCCACCGGTCTCGCCGAGATCCTCGTGCTCGTGGGCGGCTGCGACCAGGACTGTGACGAGCTGGTCACTGTCGACTGCTACAACCCGCAGACGGGTCAGTGGCGCTACCTGGCCGAGTTCCCAGACCACCTGGGCGGAGGCTACAGCATCGTGGCGCTGGGCAATGACATCTACGTGACGGGTGGGTCCGATGGCTCCCGGCTCTATGACTGCGTGTGGAGGTACAACTCAAGCGTGAATGAGTGGGCGGAGGTGGCGCCCATGCTGAAGGCCCGCGAGTACCACAGCTCCTCTGTGCTGGACGGACTGCTGTACGTGGTGGCCGCCGACAGCACCGAGCGCTATGACCACACCACTGACTCCTGGGAGGCCCTGCAGCCCATGACCTACCCCATGGACAACTGCTCCACCACTGCGTGCCGTGGCCGGCTCTATGCCATCGGCTCCCTGGCTGGCAAGGAGACCATGGTGATGCAGTGCTACGACCCGGACACCGACCTGTGGTCGCTGGTGGACTGCGGCCAGCTCCCGCCCTGGTCCTTCGCCCCCAAGACTGCGACTCTAAACGGACTCATGTACTTTGTCAGGGATGACTCCGCTGAGGTGGACGTGTACAACCCGACGAGGAACGAATGGGACAAGATCCCGTCCATGAATCAGGTACATGTGGGGGGCAGCCTGGCCGTCCTTGGGGGGAAGCTGTACGTCTCTGGGGGATACGACAATACATTTGAACTCTCGGACGTGGTAGAGGCCTATGACCCAGAGACTCGCGCGTGGAGCGTGGTGGGGCGGCTCCCAGAACCCACCTTCTGGCATGGCAGTGTCAGCATCTTCCGCCAGTTCATGCCCCAGACCTTCTCGGGTGGGCGTGGCTTCGAGTTGGACAGTGGCAGCGATGACATGGACCCAGGCCGACCCCGGCCGCCGCGGGACCCCGATGAGCTGCACTAG
Sequence Length
1794
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
60,378 Da
NCBI Official Full Name
Homo sapiens kelch-like 21 (Drosophila), mRNA
NCBI Official Synonym Full Names
kelch like family member 21
NCBI Official Symbol
KLHL21
NCBI Protein Information
kelch-like protein 21
UniProt Protein Name
Kelch-like protein 21
Protein Family
UniProt Gene Name
KLHL21
UniProt Synonym Gene Names
KIAA0469
UniProt Entry Name
KLH21_HUMAN
Uniprot Description
KLHL21: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Ubiquitin conjugating system
Chromosomal Location of Human Ortholog: 1p36.31
Cellular Component: centrosome; polar microtubule
Molecular Function: ubiquitin-protein ligase activity
Biological Process: protein ubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process; regulation of cytokinesis
Research Articles on KLHL21
Similar Products
Product Notes
The KLHL21 klhl21 (Catalog #AAA1272697) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGAGCGAC CGGCGCCCCT GGCCGTGCTT CCCTTCTCGG ACCCCGCGCA CGCCCTGAGC CTGCTGCGCG GCCTGAGCCA GCTGCGCGCC GAGCGCAAGT TCCTGGACGT GACCCTGGAG GCGGCGGGCG GGCGCGACTT CCCGGCGCAC CGTGCGGTGC TGGCCGCCGC CAGCCCCTAC TTCCGCGCCA TGTTCGCGGG GCAGCTGCGC GAGAGCCGCG CCGAGCGGGT GCGCCTGCAC GGAGTGCCTC CCGACATGCT GCAGCTGCTG CTGGACTTCA GCTACACGGG CCGCGTGGCG GTAAGCGGCG ACAACGCTGA GCCGCTGCTG CGCGCCGCCG ACCTGCTGCA GTTCCCGGCC GTGAAGGAGG CGTGCGGGGC CTTCCTGCAG CAGCAGCTCG ACCTGGCCAA CTGCCTGGAC ATGCAGGACT TCGCTGAGGC CTTCAGCTGC TCGGGACTGG CGAGCGCGGC GCAGCGGTTC ATTCTGCGCC ACGTGGGCGA GCTGGGCGCC GAGCAGCTGG AGCGGCTGCC ACTGGCGCGC CTGCTGCGCT ACCTGCGGGA CGACGGGCTG TGTGTGCCCA AGGAGGAGGC CGCCTACCAG CTGGCGCTGC GCTGGGTCCG CGCTGACCCG CCGCGCCGCG CCGCGCACTG GCCGCAGCTG CTGGAGGCCG TGCGCCTGCC CTTCGTGCGC CGCTTCTACC TGTTGGCGCA CGTCGAGGCC GAGCCGCTGG TGGCGCGCTG CCCACCCTGC CTGCGCCTGC TGCGCGAGGC GCGCGACTTC CAGGCGGCGC GCTACGACCG CCACGACCGC GGGCCCTGTC CCCGAATGCG TCCTCGCCCG TCCACCGGTC TCGCCGAGAT CCTCGTGCTC GTGGGCGGCT GCGACCAGGA CTGTGACGAG CTGGTCACTG TCGACTGCTA CAACCCGCAG ACGGGTCAGT GGCGCTACCT GGCCGAGTTC CCAGACCACC TGGGCGGAGG CTACAGCATC GTGGCGCTGG GCAATGACAT CTACGTGACG GGTGGGTCCG ATGGCTCCCG GCTCTATGAC TGCGTGTGGA GGTACAACTC AAGCGTGAAT GAGTGGGCGG AGGTGGCGCC CATGCTGAAG GCCCGCGAGT ACCACAGCTC CTCTGTGCTG GACGGACTGC TGTACGTGGT GGCCGCCGAC AGCACCGAGC GCTATGACCA CACCACTGAC TCCTGGGAGG CCCTGCAGCC CATGACCTAC CCCATGGACA ACTGCTCCAC CACTGCGTGC CGTGGCCGGC TCTATGCCAT CGGCTCCCTG GCTGGCAAGG AGACCATGGT GATGCAGTGC TACGACCCGG ACACCGACCT GTGGTCGCTG GTGGACTGCG GCCAGCTCCC GCCCTGGTCC TTCGCCCCCA AGACTGCGAC TCTAAACGGA CTCATGTACT TTGTCAGGGA TGACTCCGCT GAGGTGGACG TGTACAACCC GACGAGGAAC GAATGGGACA AGATCCCGTC CATGAATCAG GTACATGTGG GGGGCAGCCT GGCCGTCCTT GGGGGGAAGC TGTACGTCTC TGGGGGATAC GACAATACAT TTGAACTCTC GGACGTGGTA GAGGCCTATG ACCCAGAGAC TCGCGCGTGG AGCGTGGTGG GGCGGCTCCC AGAACCCACC TTCTGGCATG GCAGTGTCAG CATCTTCCGC CAGTTCATGC CCCAGACCTT CTCGGGTGGG CGTGGCTTCG AGTTGGACAG TGGCAGCGAT GACATGGACC CAGGCCGACC CCGGCCGCCG CGGGACCCCG ATGAGCTGCA CTAG. It is sometimes possible for the material contained within the vial of "KLHL21, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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