RAB11B cdna clone
RAB11B cDNA Clone
NCBI and Uniprot Product Information
NCBI Description
The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways (summary by Zhu et al., 1994 [PubMed 7811277]).[supplied by OMIM, Nov 2010]
Uniprot Description
RAB11B: GTPase that modulates endosomal trafficking. Acts as a major regulator of membrane delivery during cytokinesis. Interacts with RAB11FIP1, RAB11FIP2, RAB11FIP3 and RAB11FIP4. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric; G protein; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cell junction; cell-cell adherens junction; microtubule organizing center; phagocytic vesicle; plasma membrane; recycling endosome; synaptic vesicle
Molecular Function: GDP binding; GTP binding; GTPase activity; myosin V binding; protein binding
Biological Process: constitutive secretory pathway; melanosome transport; receptor recycling; regulated secretory pathway; transferrin transport
Research Articles on RAB11B
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Product Notes
The RAB11B rab11b (Catalog #AAA1272641) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGGGACCC GGGACGACGA GTACGACTAC CTATTCAAAG TGGTGCTCAT CGGGGACTCA GGCGTGGGCA AGAGCAACCT GCTGTCGCGC TTCACCCGCA ACGAGTTCAA CCTGGAGAGC AAGAGCACCA TCGGCGTGGA GTTCGCCACC CGCAGCATCC AGGTGGACGG CAAGACCATC AAGGCGCAGA TCTGGGACAC CGCTGGCCAG GAGCGCTACC GCGCCATCAC CTCCGCGTAC TACCGTGGTG CAGTGGGCGC CCTGCTGGTG TACGACATCG CCAAGCACCT GACCTATGAG AACGTGGAGC GCTGGCTGAA GGAGCTGCGG GACCACGCAG ACAGCAACAT CGTCATCATG CTGGTGGGCA ACAAGAGTGA CCTGCGCCAC CTGCGGGCTG TGCCCACTGA CGAGGCCCGC GCCTTCGCAG AAAAGAACAA CTTGTCCTTC ATCGAGACCT CAGCCTTGGA TTCCACTAAC GTAGAGGAAG CATTCAAGAA CATCCTCACA GAGATCTACC GCATCGTGTC ACAGAAACAG ATCGCAGACC GTGCTGCCCA CGACGAGTCC CCGGGGAACA ACGTGGTGGA CATCAGCGTG CCGCCCACCA CGGACGGACA GAAGCCCAAC AAGCTGCAGT GCTGCCAGAA CCTGTGA. It is sometimes possible for the material contained within the vial of "RAB11B, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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